[HTML][HTML] Coronavirus infection and cholesterol metabolism

J Dai, H Wang, Y Liao, L Tan, Y Sun, C Song… - Frontiers in …, 2022 - frontiersin.org
… membranes, host cell cholesterol is targeted by pathogens (… membranes, cholesterol
accumulation in lymphoid organs … in cholesterol metabolism in CD11c + immune cells resulted in …

[HTML][HTML] Comprehensive analysis of the immune infiltrates and aberrant pathways activation in atherosclerotic plaque

H Han, R Du, P Cheng, J Zhang, Y Chen… - Frontiers in …, 2021 - frontiersin.org
… Study) trial was the most noteworthy of the studies and targeted IL-1β (42). The CANTOS
trial … After a high cholesterol diet, lipid accumulation in the blood vessels of CD11c+ DCs was …

Baseline serum cholesterol levels predict the response of patients with advanced non-small cell lung cancer to immune checkpoint inhibitor-based treatment

J Tong III, Y Mao, Z Yang, Q Xu, Z Zheng… - Cancer Management …, 2021 - Taylor & Francis
… After chemotherapy and targeted therapy, immune-… , high serum cholesterol interacted with
immune cells to enhance their … cells, accumulation of cholesterol induced the expression of …

[HTML][HTML] The multifaceted impact of complement on atherosclerosis

MG Kiss, CJ Binder - Atherosclerosis, 2022 - Elsevier
… events - although no causality has been established to link CRP … Cholesterol crystals
accumulate early in the vessel wall and … targeted, cell-specific inhibitory approaches are …

Novel mechanisms and therapeutic targets in atherosclerosis: inflammation and beyond

C Weber, AJR Habenicht… - European heart …, 2023 - academic.oup.com
Immune cell recruitment can be targeted by specific … in atherogenesis triggered by cholesterol
crystals, disturbed flow, … in CD11c+ dendritic cells. Thus, expression of CD40L in CD4+ T …

Pharmacological targets of metabolism in disease: opportunities from macrophages

A Castegna, R Gissi, A Menga, M Montopoli… - Pharmacology & …, 2020 - Elsevier
… of the immune system, it is emerging that the specialized functions displayed by macrophages
during the course of an immune … , such as diabetes, sepsis, cancer, and autoimmunity. The …

Cellular lipids in B cell immunity, inflammation, and cancer

Y Zhang, JM Ntambi, D Fang - Cellular Lipid in Health and Disease, 2023 - Elsevier
… causes a variety of autoimmune diseases due to the production … that targeted ablation of
Acat1 gene, which converts cellular … Indeed, it has been shown that cholesterol accumulation in …

[HTML][HTML] Immunomodulatory actions of vitamin D in various immune-related disorders: a comprehensive review

A Ghaseminejad-Raeini, A Ghaderi, A Sharafi… - Frontiers in …, 2023 - frontiersin.org
… Seven-dehydrogenated cholesterol undergoes spontaneous … mediated inflammation and
CD11c + major histocompatibility … of vitamin D on T cells, they can be targeted directly, too (196)…

[HTML][HTML] Kupffer cells dictate hepatic responses to the atherogenic dyslipidemic insult

G Di Nunzio, S Hellberg, Y Zhang, O Ahmed… - Nature Cardiovascular …, 2024 - nature.com
cells and rapid accumulation of triglycerides and cholesterol … (LDL), are the causal agents
of atherosclerosis due to their … on both sides of the targeted locus. Recombined ESC clones …

The comprehensive role of apoptosis inhibitor of macrophage (AIM) in pathological conditions

H Yang, Y Luo, X Lai - Clinical and Experimental Immunology, 2023 - academic.oup.com
… AIM inhibited cholesterol synthesis by regulating key … In vitro and in vivo studies of
gene-targeted mice have shown … membrane and accumulated on debris of dead cells in the lumen …