… disease course. We address these challenges in a detailed review of the noradrenergic and
cholinergic … they influence neuropsychiatric symptoms in disease. By bridging across levels …

… then released into the synapse, where it binds to cholinergic … of cholinergic transmission,
such as the diffusion of ACh from … The latter limit ACh release following a rapid increase in ACh …

… which are capable of both abolishing NE release and inducing cholinergic marker (choline
acetyltransferase -ChAT and vesicular acetylcholine transporter- VaChT) synthesis in cardiac …

Dysregulated homeostasis of neural activity has been hypothesized to drive Alzheimer's
disease (AD) pathogenesis. AD begins with a decades-long presymptomatic phase, but …

… cerebrovascular health biomarkers such as cerebral autoregulation, CVR, and NVC will be
… cholinergic or sympathetic cholinergic nerves, both of which release acetylcholine (ACh) as …

… TrkA, on pre-synaptic cholinergic neurons, NGF gets to the … cascade for the release of
acetylcholine. NGF maturation … Cerebrovascular autoregulation maintains the CBF despite …

… cholinergic system in various neurodegenerative diseases … Acetylcholine is synthesized
within cholinergic neurons from … disease-specific pathology, such as in Alzheimer's disease (AD)…

… have been reported in neurodegenerative disorders such as Alzheimer's disease (AD). …
mice, sections were immunostainned with cholinergic markers. ACh, one of the major excitatory …

… 70 Following bilateral ganglionectomy, an impairment in the autoregulatory function in the …
PI turnover via presynaptic M2-GIRK-related ACh release. Additionally, the Basal phase of this …

… released ACh and reduce the cholinergic receptor activation. Since decreased acetylcholine
leads to Alzheimer's disease… to enhance the amount of acetylcholine in the synaptic cleft [30]…