Nicotine Pretreatment Increases Sensitivity to Reward Devaluation in Extinction

AP Kirshenbaum, A Kristofik, H Geick… - The Psychological …, 2021 - Springer
… of satiety conditions. However, the lack of observable somatic symptoms of withdrawal
may … these effects are systematically related to nicotinic-acetylcholine-receptor occupation. …

Mechanism of opioid addiction and its intervention therapy: Focusing on the reward circuitry and mu‐opioid receptor

JJ Zhang, CG Song, JM Dai, L Li, XM Yang… - MedComm, 2022 - Wiley Online Library
… the abused drugs, and abstinence reactions here are equal to withdrawal reactions or
withdrawal … Selective activation of MORs in cholinergic interneurons in the dorsal lateral striatum …

Physiological role of orexinergic system for health

I Villano, M La Marra, G Di Maio, V Monda… - International Journal of …, 2022 - mdpi.com
… Orexins stimulate BF cholinergic and non-cholinergic neurons in response to salient stimuli
… the modulation of hunger and satiety signals [108,109]. The preference for agreeable food is …

Neuroplasticity and multilevel system of connections determine the integrative role of nucleus accumbens in the brain reward system

M Bayassi-Jakowicka, G Lietzau, E Czuba… - International Journal of …, 2021 - mdpi.com
… On the other hand, prolonged ethanol withdrawal caused a reduction of the NMDARs …
responsible for acetylcholine (ACh) production. In these areas, GABA has a modulating effect upon …

Pharmacologic management of obesity‐updates on approved medications, indications and risks

C Lupianez‐Merly, S Dilmaghani… - Alimentary …, 2024 - Wiley Online Library
… of appetite, satiety, satiation, and food intake is paramount. This … Vagal cholinergic
afferents also arise from other … on withdrawal of the medications. In a randomised, double-blind, …

Obesity–an update on the basic pathophysiology and review of recent therapeutic advances

E Gjermeni, AS Kirstein, F Kolbig, M Kirchhof… - Biomolecules, 2021 - mdpi.com
… ] and PP activates vagal cholinergic pathways in the brainstem via … affects glucose homeostasis,
food intake, and satiety. It is … EMA approval, the drug had to be withdrawn because of the …

[HTML][HTML] New developments in prokinetic therapy for gastric motility disorders

M Camilleri, J Atieh - Frontiers in Pharmacology, 2021 - frontiersin.org
… Cisapride is no longer available in most countries due to withdrawal as a result of … of food
from the stomach since, as a motilin receptor agonist and stimulant of cholinergic mechanisms, …

Bacteroides uniformis CECT 7771 Modulates the Brain Reward Response to Reduce Binge Eating and Anxiety-Like Behavior in Rat

A Agustí, I Campillo, T Balzano, A Benítez-Páez… - Molecular …, 2021 - Springer
… from drug addiction in that food is essential for life and there is no chemical withdrawal
uniformis on BE and behavior was mediated by changes in appetite/satiety signals, we evaluated …

Improved satiety signalling in obesity with a novel combination treatment of Caralluma fimbriata Extract and Lorcaserin

VBSC Thunuguntla - 2022 - vuir.vu.edu.au
… crucial role in balancing hunger and satiety for an individual. The hypothalamus's
arcuate … concerns about side effects and it was withdrawn from sale in the USA in 2020. …

[HTML][HTML] Modulation of GABA release by 5-HT1B receptors: An interplay with AMPA-receptors and voltage-gated Ca2+ channels

DAN Al-Halboosi, O Savchenko, LK Heisler… - …, 2023 - Elsevier
… intake and as such has been the target of obesity medications. However, key mechanisms
… stimulators of hunger and food intake. NAG neurons also inhibit local satiety-promoting pro-…