Acute, chronic and conditioned effects of intranasal oxytocin in the mu opioid receptor knockout mouse model of autism: social context matters

F Pantouli, C Pujol, C Derieux, M Fonteneau… - bioRxiv, 2024 - biorxiv.org
… the effects of acute intranasal OT in Oprm1 null mice, we assessed the effects of this treatment
on social preference and social … , Chronic and acute intranasal oxytocin produce divergent

Effects of intranasal administration of oxytocin and vasopressin on social cognition and potential routes and mechanisms of action

S Yao, KM Kendrick - Pharmaceutics, 2022 - mdpi.com
Acute and chronic administration of intranasal oxytocin and vasopressin … the mouse
characterized by high OXTR density following intranasal administration of OXT, although a divergent

Acute and repeated intranasal oxytocin differentially modulate brain-wide functional connectivity

M Pagani, A De Felice, C Montani, A Galbusera… - Neuroscience, 2020 - Elsevier
mice upon acute and repeated (seven-day) intranasal dosing of OXT. We report that acute
and chronic … Such divergent patterns of network connectivity might contribute to discrepant …

Chronic intranasal oxytocin reverses stress-induced social avoidance in female prairie voles

LH Hale, MC Tickerhoof, AS Smith - Neuropharmacology, 2021 - Elsevier
… ) which produce peripheral effects in mice and rats via peripheral oxytocin receptor activation
… and OXT administration present an interesting divergence of the neurobiology underlying a …

Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
… substrates engaged by acute intranasal oxytocin in mice and … that intranasal oxytocin
seems to have divergent effectschronic administration of oxytocin will emerge as a long-term

[HTML][HTML] Examining the effect of chronic intranasal oxytocin administration on the neuroanatomy and behavior of three autism-related mouse models

Z Lindenmaier, J Ellegood, M Stuive, K Easson, Y Yee… - NeuroImage, 2022 - Elsevier
… Therefore, to determine whether oxytocin changes brain circuitry, and whether it does so …
study on chronic intranasal oxytocin treatment in three different mouse models related to autism …

Effects of Chronic and Acute Intranasal Oxytocin Treatments on Temporary Social Separation in Adult Titi Monkeys (Plecturocebus cupreus)

R Arias del Razo, ML Velasco Vazquez… - Frontiers in Behavioral …, 2022 - frontiersin.org
long-term effects on adult social behavior. In the current study, we examined the chronic and
acute effectsChronic IN OXT treatment in mice has led to decreased OXTRs throughout the …

Intranasal oxytocin in a genetic animal model of autism

J Szabó, M Mlynár, A Feješ, E Renczés… - Molecular …, 2023 - nature.com
… We demonstrated that chronic intranasal OXT exposure can reliably ameliorate social
deficits in the Shank3B −/− mouse model of autism as early as after 2 weeks of administration. …

Oxytocin—a social peptide? Deconstructing the evidence

G Leng, RI Leng, M Ludwig - … Transactions of the …, 2022 - royalsocietypublishing.org
… in male rats, icv or peripheral injections of oxytocin could shorten … the reported effects of
intranasal oxytocin are all true effects, … oxytocin as a therapy for social anxiety, noting that chronic

Anxiolytic effects of chronic intranasal oxytocin on neural responses to threat are dose-frequency dependent

J Kou, Y Zhang, F Zhou, Z Gao, S Yao… - Psychotherapy and …, 2022 - karger.com
… Moreover, divergent effects on the behavioral and neural levels may be explained in terms
of differences in the brain systems and behavioral processes underlying implicit emotional …