Copper–zinc imbalance induces kidney tubule damage and oxidative stress in a population exposed to chronic environmental cadmium

SY Eom, DH Yim, M Huang, CH Park, GB Kim… - International archives of …, 2020 - Springer
… Satarug S, Nishijo M, Ujjin P, Moore MR (2018) Chronic exposure to low-level cadmium
induced zinc-copper dysregulation. J Trace Elem Med Biol Organ Soc Miner Trace Elem (GMS) …

Gender differences in zinc and copper excretion in response to co-exposure to low environmental concentrations of cadmium and lead

S Satarug, GC Gobe, P Ujjin, DA Vesey - Stresses, 2020 - mdpi.com
… in an area of low-level environmental exposure to Cd and Pb, … Evidence for dysregulation
of Zn and Cu homeostasis has … function deterioration due to chronic exposure to Cd and Pb. …

Modulation of Adverse Health Effects of Environmental Cadmium Exposure by Zinc and Its Transporters

A Cirovic, A Cirovic, S Yimthiang, DA Vesey, S Satarug - Biomolecules, 2024 - mdpi.com
… excretion to reflect the long-term exposure or body burden of Cd … Dysregulated metal
homeostasis, evident from reduced … population exposed to a very low level of Cd like Sweden …

The evolving role for zinc and zinc transporters in cadmium tolerance and urothelial cancer

S Satarug, DA Vesey, GC Gobe - Stresses, 2021 - mdpi.com
… Of note, dysregulated cellular Zn homeostasis and aberrant … postulated to explain how
chronic exposure to Cd increases cancer … that chronic exposure to low-level Cd induces cellular …

Mechanisms of cadmium neurotoxicity

MA Arruebarrena, CT Hawe, YM Lee… - International Journal of …, 2023 - mdpi.com
… vulnerable to prolonged, low-dose cadmium exposure. This … Furthermore, cadmium induces
the opening of the permeability … Zinc dysregulation induced by cadmium may be a risk factor …

Is cadmium toxicity tissue-specific? Toxicogenomics studies reveal common and specific pathways in pulmonary, hepatic, and neuronal cell models

M Forcella, P Lau, M Fabbri, P Fusi, M Oldani… - International Journal of …, 2022 - mdpi.com
caused by the interplay of Cd and Ca and the dysregulationexposure reduces DNA
methylation, while chronic exposure … were not detected or detected at low level. A normalized log2 …

Biological effects of human exposure to environmental cadmium

M Peana, A Pelucelli, CT Chasapis, SP Perlepes… - Biomolecules, 2022 - mdpi.com
chronic exposure causes harmful effects from the metal stored in the organs. The present
paper considers exposure … (GPx) leads to the further dysregulation of the cellular redox state [3,…

Systemic copper disorders influence the olfactory function in adult rats: roles of altered adult neurogenesis and neurochemical imbalance

SXF Adamson, W Zheng, ZS Agim, S Du, S Fleming… - Biomolecules, 2021 - mdpi.com
… The buried pellet test revealed both CuD and CuO prolonged the latency to uncover food. …
Clinical evidence also suggests an olfactory dysregulation in patients with Cu-homeostasis …

Effects of Copper and Zinc Supplementation on Haematological, Renal and Liver Function in Healthy Wistar Rats

E Effah-Yeboah, EA Asare… - Asian Journal …, 2021 - journal.scienceopenlibraries.com
Long-term exposure to these trace elements can lead to a lot of pathologies. … Chronic
exposure to low-level cadmiuminduced zinc-copper dysregulation. Journal of Trace Elements in …

Prolonged Cadmium Exposure and Osteoclastogenesis: A Mechanistic Mouse and in Vitro Study

Z Liu, J Wu, Z Dong, Y Wang, G Wang… - Environmental …, 2024 - ehp.niehs.nih.gov
… Human long-term exposure to Cd, which occurs mainly from consumption of contaminated
… The effects of low-level cadmium (Cd) exposure on osteoclastogenesis in BM-OPCs and …