Improving chromatin-interaction prediction using single-cell open-chromatin profile and making insight about the cis-regulatory landscape of the human brain

N Pandey, O Chandra, S Mishra, V Kumar - bioRxiv, 2020 - biorxiv.org
single-cell Epigenome based chromatin-interaction Analysis (scEChIA) which can predict
interactions … We found that scEChIA is as accurate as Cicero, whereas using constant ρ value …

[HTML][HTML] Improving chromatin-interaction prediction using single-cell open-chromatin profiles and making insight into the cis-regulatory landscape of the human brain

N Pandey, O Chandra, S Mishra, V Kumar - Frontiers in Genetics, 2021 - frontiersin.org
… -Accessible Chromatin using sequencing (scATAC-seq) profile. However, Cicero is designed
for predicting interactions … called jointly reconstruct cis-regulatory interaction maps (JRIM) (…

DIRECT-NET: An efficient method to discover cis-regulatory elements and construct regulatory networks from single-cell multiomics data

L Zhang, J Zhang, Q Nie - Science advances, 2022 - science.org
… or from single-cell chromatin accessibility data alone. By … ’s predicted CREs using independent
functional genomics data, we … , Cicero quantifies how changes in chromatin accessibility

Characterizing cis-regulatory elements using single-cell epigenomics

S Preissl, KJ Gaulton, B Ren - Nature Reviews Genetics, 2023 - nature.com
… Activity of distal and proximal CREs can also be used to predict … While cytosine methylation
can prevent DNA binding by … Single-cell chromatin accessibility profiling has been widely …

[PDF][PDF] A cis-regulatory atlas in maize at single-cell resolution

AP Marand, Z Chen, A Gallavotti, RJ Schmitz - Cell, 2021 - cell.com
… We measured chromatin accessibility and nuclear gene … To corroborate predicted cell-type
annotations, we … distinct cell-types, we used Cicero to estimate gene activity scores. …

Joint reconstruction of cis-regulatory interaction networks across multiple tissues using single-cell chromatin accessibility data

K Dong, S Zhang - Briefings in Bioinformatics, 2021 - academic.oup.com
… have been developed to estimate cis-regulatory DNA interactions using epigenetic data [14–18]. …
For example, Cicero [26] employs a graphical lasso model to detect linkages between …

[HTML][HTML] ChromaFold predicts the 3D contact map from single-cell chromatin accessibility

VR Gao, R Yang, A Das, R Luo, H Luo, DR McNally… - bioRxiv, 2023 - ncbi.nlm.nih.gov
single-cell chromatin accessibility data and make cell-type-specific contact map predictions.
… of peak-level significant interaction prediction using Cicero co-accessibility at various cutoffs …

Exploring plant cis‐regulatory elements at singlecell resolution: overcoming biological and computational challenges to advance plant research

JP Mendieta, A Sangra, H Yan, MAA Minow… - The Plant …, 2023 - Wiley Online Library
… the application of single-cell epigenomic data in various contexts … A rapid and robust method
for single cell chromatin accessibilityCicero Predicts cis-Regulatory DNA Interactions from …

Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen

Z Li, C Kuppe, S Ziegler, M Cheng, N Kabgani… - Nature …, 2021 - nature.com
… -seq data as clustering, visualization, cis-regulatory DNA … We compared Cicero predicted
interactions on human … scATAC-seq is the prediction of cis-regulatory DNA interactions (peak-to-…

Single-cell analysis of cis-regulatory elements

AP Marand, RJ Schmitz - Current Opinion in Plant Biology, 2022 - Elsevier
… Owing to steric requirements of most DNA binding proteins, … in maize was able to predict
cell-type annotations with high … chromatin accessibility through comparison of single-cell