Systemic therapy for mucosal, acral, and uveal melanoma
… melanoma cohort of the Phase I study of IMCgp100, a recombinant T-cell receptor that recognizes
the melanoma … , also showed early promising results with 3 patients (20%) achieving a …
the melanoma … , also showed early promising results with 3 patients (20%) achieving a …
[HTML][HTML] … inhibition therapy for advanced skin cancer in patients with concomitant hematological malignancy: a retrospective multicenter DeCOG study of 84 patients
U Leiter, C Loquai, L Reinhardt… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
… plus paclitaxel or gemcitabine plus treosulfan; patients with advanced … (cSCC) received
carboplatin, cisplatin, paclitaxel, or … In CLL patients, the cumulative recurrence rate of cSCC at 8 …
carboplatin, cisplatin, paclitaxel, or … In CLL patients, the cumulative recurrence rate of cSCC at 8 …
Systemic and liver-directed therapies in metastatic uveal melanoma: State-of-the-art and novel perspectives
F Comito, PV Marchese, AD Ricci, N Tober… - Future …, 2021 - Taylor & Francis
… , treosulfan and cisplatin, in association with gemcitabine. … patients with inoperable stage
III or stage IV melanoma of … in 32 patients with recurrent or metastatic UM in a phase II study, …
III or stage IV melanoma of … in 32 patients with recurrent or metastatic UM in a phase II study, …
New therapeutic perspectives in the treatment of uveal melanoma: A systematic review
… For brachytherapy, reported local recurrence rates are 14.7%—for 106Ru treatment, 7%–10…
drug was stopped after the first dose due to the onset of a severe form of diabetes (grade 4). …
drug was stopped after the first dose due to the onset of a severe form of diabetes (grade 4). …
[PDF][PDF] New therapeutic perspectives in the treatment of uveal melanoma: a systematic review. Biomedicines 2021; 9: 1311
… included recurrent grade 3 proteinuria, grade 4 … The median OS was worst in patients
receiving treosulfan/gemcitabine as … The combination therapy of treosulfan/gemcitabine was well …
receiving treosulfan/gemcitabine as … The combination therapy of treosulfan/gemcitabine was well …
Extracutaneous melanoma
R Carvajal, R Maniar - Hematology/Oncology Clinics, 2021 - hemonc.theclinics.com
… A randomized phase II study in China evaluated observation … with temozolomide and cisplatin
in patients with stage I/II MM … late relapses can occur, with 20% to 30% of patients dying of …
in patients with stage I/II MM … late relapses can occur, with 20% to 30% of patients dying of …
Molecular insights and emerging strategies for treatment of metastatic uveal melanoma
F Mallone, M Sacchetti, A Lambiase, A Moramarco - Cancers, 2020 - mdpi.com
… -γ-adenovirus in cutaneous metastatic melanoma is ongoing [… treosulfan or cisplatin,
gemcitabine and treosulfan, cisplatin, … in a small group of patients relapsing after complete first …
gemcitabine and treosulfan, cisplatin, … in a small group of patients relapsing after complete first …
[HTML][HTML] European consensus-based interdisciplinary guideline for melanoma. Part 2: treatment–update 2019
, … Association of Dermato-Oncology (EADO - European Journal of …, 2020 - Elsevier
… 4 antibodies shall be considered. In particular scenarios for patients with stage IV melanoma
… that despite a slight increase in recurrence-free survival in patients undergoing SLNB, it has …
… that despite a slight increase in recurrence-free survival in patients undergoing SLNB, it has …
Systemic Therapy for Metastatic Uveal Melanoma
EH Bernicker - Uveal Melanoma: Biology and Management, 2021 - Springer
… While the ability to identify patients at high risk of recurrence … The combination of treosulfan
and gemcitabine in metastatic … of cisplatin, vindesine, and dacarbazine had seemed in phase …
and gemcitabine in metastatic … of cisplatin, vindesine, and dacarbazine had seemed in phase …
A Phase 1 study of ADI‐PEG20 (pegargiminase) combined with cisplatin and pemetrexed in ASS1‐negative metastatic uveal melanoma
… For instance, the median OS for the triplet drug combination of cisplatin, treosulfan and
gemcitabine was 6 months only in relapsed UM (Atzpodien et al., 2008). Radioembolisation with …
gemcitabine was 6 months only in relapsed UM (Atzpodien et al., 2008). Radioembolisation with …