… of their elevated urinary concentration and their proved clinical efficacy [Citation25]. … New
drugs for the treatment of urinary infections are strongly warranted. An ideal new antibiotic …

… in treating complicated urinary tract infections (cUTI), complicated intra-abdominal infections
and … *Enhanced stability to β-lactamases does not always correlate with clinical efficacy. …

… of antibiotics for treatment of cUTI can improve clinical outcomes and decrease mortality and
healthcare costs. [1] Treatment guidance for urinary tract infections … and empiric treatment of …

… It is important to use the new antimicrobials wisely for treatment of UTIs caused by MDR-…
However, there is very limited data on its clinical efficacy in the treatment of UTIs and debate on …

… as infection models for the study of novel antibiotics, … of infections, such as host–pathogen
interactions and evolutionary mechanisms of infection, and for developing novel antibiotics …

… (MDR infection vs any infection), type of infection (eg, urinary tract … , new antibiotics are
sometimes approved for marketing with limited data regarding clinical efficacy against infections …

… robust results to date and appear to be the most promising new alternative to currently
used antibiotics. Larger efficacy clinical trials as well as studies on the interplay between non-…

… The primary outcome was clinical efficacy, which was defined as the clinical response
assessed during follow-up after treatment. Outcomes were assessed in terms of complete …

… oral options and highlighting an unmet need for novel antibiotics to treat these infections (5). …
optimal antibiotic dosing regimens that are most likely to demonstrate clinical efficacy and …

… evaluated the efficacy and safety of orally administered tebipenem pivoxil hydrobromide as
compared with intravenous ertapenem in patients with complicated urinary tract infection or …