Significance of 5-S-Cysteinyldopa as a Marker for Melanoma

K Wakamatsu, S Fukushima, A Minagawa… - International Journal of …, 2020 - mdpi.com
… in monitoring of patients with metastatic melanoma receiving … melanoma and reported the
clinical significance of 5SCD [… repeated every other month with monitoring of 5SCD level in …

[HTML][HTML] Combination of serum 5-S-cysteinyldopa, melanoma inhibitory activity and IL-8 improves the diagnostic accuracy of malignant melanoma compared with …

Y Katoh, H Hara, T Harada, S Hirai - Medicine, 2022 - journals.lww.com
… of malignant melanoma and monitoring its treatment. [ 31 ] Other studies reported a significant
… were significantly reduced in stage IV melanoma patients who respond to chemotherapy, [ …

Metabolic basis and clinical evidence for skin lightening effects of thiol compounds

YC Boo - Antioxidants, 2022 - mdpi.com
… Many studies have used colorimetric methods monitoring the production of dopachrome …
an increase in eumelanin synthesis as seen in human melanoma cells [102]. Conversely, …

A method for measuring serum levels of melanin-associated indole metabolites using LC-MS/MS and its application to malignant melanoma

M Takiwaki, H Umemura, Y Kikutani, S Fukuzawa… - Clinica Chimica …, 2024 - Elsevier
Background and aims With the development of novel therapies for advanced malignant
melanoma (MM), biomarkers that can accurately reflect the progression of MM are needed. …

Determination of the Degradation Products of Pheomelanin as Potential Biomarker for Early-Stage Melanoma by Gas Chromatography-Mass Spectrometry (GC-MS)

W Cheng, JH Lee, E Miller, B Jackson - Analytical Letters, 2024 - Taylor & Francis
5-S-cysteinyldopa (5SCD) exhibits promising potential as a urinary and serum biomarker
for melanoma… Furthermore, it is noteworthy that the clinical implications stemming from this …

Dopamine and L-Dopa as Selective Endogenous Neurotoxins

J Segura-Aguilar, U Ahumada-Castro, I Paris - Handbook of Neurotoxicity, 2021 - Springer
… more than thousand studies described malignant melanoma as the most frequent oral …
5-S-cysteinyldopa formation by tyrosinase activity and intracellular thiols in human melanoma

Molecular events in the melanogenesis cascade as novel melanoma-targeted small molecules: Principle and development

K Wakamatsu, A Ito, Y Tamura, T Hida, T Kamiya… - Cancers, 2022 - mdpi.com
… Following those efforts by Wick’s group, Fujita et al. reported that 5-S-cysteinyldopa (5SCD), …
few cancer-antigens and escape from host surveillance for neoplasms. One of the potential …

[HTML][HTML] IMMU-09. NIVOLUMAB THERAPY FOR A PEDIATRIC-ONSET PRIMARY INTRACRANIAL MELANOMA

U Oba, Y Koga, R Kawaguchi, K Nakashima… - Neuro …, 2020 - researchgate.net
… , cerebrospinal fluid 5-S-cysteinyldopa levels declined and … , but it had little clinical
significance. Vonoprazan can be … We could monitor eight novel antiepileptics using an LC/MS …

Promising blood-based biomarkers for melanoma: Recent progress of liquid biopsy and its future perspectives

H Kanemaru, Y Mizukami, A Kaneko, I Kajihara… - … Treatment Options in …, 2022 - Springer
… diagnosing and monitoring patients with melanoma during … has prognostic value in patients
with melanoma, and it might … the tumor burden in patients with melanoma was reported [13…

Promising and Minimally Invasive Biomarkers: Targeting Melanoma

P Spiliopoulou, CD Holanda Lopes, A Spreafico - Cells, 2023 - mdpi.com
… Herein, we provide an overview of circulating and other minimally invasive biomarkers
for therapeutic monitoring of patients with melanoma. In particular, the use of nucleic acids, …