Clopidogrel plus aspirin vs aspirin alone in patients with acute mild to moderate stroke: the ATAMIS randomized clinical trial

HS Chen, Y Cui, XH Wang, YT Ma, J Han… - JAMA …, 2024 - jamanetwork.com
Importance Dual antiplatelet therapy has been demonstrated to be superior to single
antiplatelet in reducing recurrent stroke among patients with transient ischemic attack or
minor stroke, but robust evidence for its effect in patients with mild to moderate ischemic
stroke is lacking. Objective To evaluate whether dual antiplatelet therapy is superior to
single antiplatelet among patients with mild to moderate ischemic stroke. Design, Setting,
and Participants This was a multicenter, open-label, blinded end point, randomized clinical …
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