Colistin monotherapy versus combination therapy for carbapenem-resistant organisms

KS Kaye, D Marchaim, V Thamlikitkul, Y Carmeli… - NEJM …, 2022 - evidence.nejm.org
colistin be combined with a carbapenem for the treatment of infections caused by
carbapenem-resistant … therapy with colistin and either rifampin 18,19 or fosfomycin 20 for invasive …

[HTML][HTML] … activity of a combination of meropenem, colistin, tigecycline, rifampin, and ceftolozane/tazobactam against carbapenem-resistant Acinetobacter baumannii

YG Ju, HJ Lee, HS Yim, MG Lee, JW Sohn, YK Yoon - Scientific reports, 2022 - nature.com
combinations against carbapenem-resistant Acinetobacter baumannii (CRAB) isolates. The
in vitro activity of six two-drug combinations … two-drug combinations against CRAB isolates. …

[HTML][HTML] Systematic review and meta-analysis of in vitro efficacy of antibiotic combination therapy against carbapenem-resistant Gram-negative bacilli

L Scudeller, E Righi, M Chiamenti, D Bragantini… - International journal of …, 2021 - Elsevier
colistin/imipenem [71] and colistin/doripenem [96]. These results were not confirmed for
combination of colistin … 0.91 were confirmed for colistin and rifampicin combination both in PK/PK …

[HTML][HTML] Effectiveness of colistin with rifampicin and meropenem against colistin-resistant Acinetobacter baumannii strains: An in vitro study

A Mosca, L Dalfino, F Romanelli… - …, 2020 - pharmacophorejournal.com
… of colistin for the treatment of carbapenem-resistant Acinetobacter baumannii infections has
led to the emergence of colistin … of colistin/rifampicin and colistin/meropenem combinations

Cefiderocol-compared to colistin-based regimens for the treatment of severe infections caused by carbapenem-resistant Acinetobacter baumannii

M Falcone, G Tiseo, A Leonildi… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
… Until now, colistin (usually combined to other drugs such as tigecycline, ampicillin/sulbactam,
meropenem or fosfomycin) has been considered the backbone therapy despite its …

[HTML][HTML] … of Loading Dose Colistin–Meropenem versus Loading Dose Colistin–Imipenem in the Treatment of Carbapenem-Resistant Acinetobacter baumannii …

W Katip, P Oberdorfer, N Kasatpibal - Pharmaceutics, 2022 - mdpi.com
… that combinations of LD colistin and meropenem should be considered when treating CRAB
… ’s synergy with a variety of antibiotics, including imipenem, meropenem, rifampin, fosfomycin…

[HTML][HTML] In Vitro Synergistic Activity of Antimicrobial Combinations against Carbapenem- and Colistin-Resistant Acinetobacter baumannii and Klebsiella pneumoniae

P Mantzana, E Protonotariou, A Kassomenaki… - Antibiotics, 2023 - mdpi.com
combinations against carbapenem-resistant and colistin-… combinations of colistin with
either meropenem or rifampicin … pneumoniae were tested for the combinations of colistin with …

[HTML][HTML] … and nephrotoxicity of colistin alone versus colistin plus vancomycin in critically ill patients infected with carbapenem-resistant Acinetobacter baumannii: a …

W Katip, P Oberdorfer - Pharmaceutics, 2021 - mdpi.com
… groups, so colistin combination with vancomycin was not necessary for the management of
… patient which was successful with the combination colistin plus vancomycin plus rifampin for …

The efficacy of colistin monotherapy versus combination therapy with other antimicrobials against carbapenem-resistant Acinetobacter baumannii ST2 isolates

J Li, Y Fu, J Zhang, Y Zhao, X Fan, L Yu… - Journal of …, 2020 - Taylor & Francis
… the efficacy of colistin both alone and in combination with either … The combination of colistin
and meropenem displayed the … , while the colistin-levofloxacin combination showed a higher …

[HTML][HTML] … and phenotypic mechanisms underlying antimicrobial resistance and synergistic efficacy of rifampicin-based combinations against carbapenem-resistant …

LC Nwabor, A Chukamnerd, OF Nwabor, K Surachat… - Heliyon, 2024 - cell.com
… , polymycin B, and colistin for the management and treatment of carbapenem-resistant A.
baumannii. It also investigates the mechanism mediating resistance to diverse antibiotics. …