Drug-loaded implantable surgical cavity-adaptive hydrogels for prevention of local tumor recurrence

B Zhuang, T Chen, Z Xiao, Y Jin - International journal of pharmaceutics, 2020 - Elsevier
… locally implanted dual drug-loaded cavity-adaptive hydrogel … in situ forming hydrogel as a
post-breast tumor resection implant. … pieces of hydrogels, including yellow and blue hydrogels, …

[HTML][HTML] Gold nanorods and nanohydroxyapatite hybrid hydrogel for preventing bone tumor recurrence via postoperative photothermal therapy and bone regeneration …

J Liao, K Shi, Y Jia, Y Wu, Z Qian - Bioactive materials, 2021 - Elsevier
… caused by the surgical resection of bone tumor (Scheme 1B). … hydrogel was then implanted
for photothermal treatment to … of the residual bone tumor containing hybrid hydrogel quickly …

Multifunctional injectable hydrogels for three-in-one cancer therapy: Preoperative remission via mild photothermal-enhanced supramolecular chemotherapy and …

J Chen, H Gu, S Fu, J Lu, H Tan, Q Wei, H Ai - Chemical Engineering …, 2021 - Elsevier
… H&E staining of the implanted hydrogel and the surrounding skin … , including tumor remission
before surgery and prevention of tumor recurrence and abdominal adhesion after resection. …

In situ gel implant for postsurgical wound management and extended chemoimmunotherapy against breast cancer recurrence

M Wang, S Wang, Y Pan, R Yu, ZR Zhang, Y Fu - Acta Biomaterialia, 2022 - Elsevier
… therapeutics at the tumor site, a photocrosslinked hydrogel (D… inflammatory cytokines,
including tumor necrosis factor α (… Collectively, the implanted D/T gel prevented recurrent tumor

Inhibition of tumor recurrence and metastasis via a surgical tumor-derived personalized hydrogel vaccine

Y Lu, C Wu, Y Yang, X Chen, F Ge, J Wang… - Biomaterials …, 2022 - pubs.rsc.org
… This combination therapy strategy could effectively inhibit the … , we implanted the hydrogels
during the surgical removal of … Each hydrogel contained 1 μg of GM-CSF or 0.1 mg of tumor

[HTML][HTML] Photothermal hydrogel platform for prevention of post-surgical tumor recurrence and improving breast reconstruction

X Yang, L Gao, Y Wei, B Tan, Y Wu, C Yi… - Journal of …, 2021 - Springer
… of the syringe and the implantation of the materials, which was a … removal; c The hydrogel
platform was injected into the tumor … cavity after breast surgery, and the contained porous MPs …

[HTML][HTML] … of 5-fluorouracil and cis-platinum via biodegradable thermo-sensitive hydrogel for intraoperative synergistic combination chemotherapy of gastric cancer

W Chen, K Shi, J Liu, P Yang, R Han, M Pan, L Yuan… - Bioactive materials, 2023 - Elsevier
… gastric cancer, the curative effect of surgical resection is … the need for invasive surgery and
implantation procedures [27,28]. … Notably, the inserts containing hydrogel were kept at 37 C for …

Advances and trends of hydrogel therapy platform in localized tumor treatment: A review

B Tan, L Huang, Y Wu, J Liao - Journal of Biomedical Materials …, 2021 - Wiley Online Library
… Such as the PEGDA hydrogel containing methylene blue … in surgical resection and GemC
12 -LNC hydrogel implantation … of combined therapy in clinical GBM after treatment regimen. …

Supramolecular hydrogel based post-surgical implant system for hydrophobic drug delivery against glioma recurrence

MV Wanjale, V Sunil Jaikumar… - International Journal …, 2022 - Taylor & Francis
… post-surgical tumor cavity, we could see a reduction in tumor … According to the authors
having a lower G’ than resected … Citation46 In this study, PCL-PEG hydrogel was implanted in …

Inhibition of post-surgery tumour recurrence via a hydrogel releasing CAR-T cells and anti-PDL1-conjugated platelets

Q Hu, H Li, E Archibong, Q Chen, H Ruan… - Nature biomedical …, 2021 - nature.com
… —through the implantation of a hyaluronic acid hydrogel—of … a, Schematic of the tumour
resection model and implantation … All data generated in this study, including source data and …