Reactive oxygen species in modulating intestinal stem cell dynamics and function

A Nath, P Chakrabarti, S Sen, A Barui - Stem Cell Reviews and Reports, 2022 - Springer
via Kelch-like ECH-associated protein 1 (subunit of cullin 3 … ROS-dependent signal pathway
and protein modulation are … the commensal autochthonous bacteria to thrive and induce …

A trans-kingdom T6SS effector induces the fragmentation of the mitochondrial network and activates innate immune receptor NLRX1 to promote infection

J Sá-Pessoa, S López-Montesino… - Nature …, 2023 - nature.com
reactive oxygen species (ROS). NLRX1-induced ROS limits NF-κB activation by modulating
… manner in a process abrogating the post-translational modification of cullin-1 with NEDD8. …

[HTML][HTML] Host directed therapy against infection by boosting innate immunity

P Bergman, R Raqib, RS Rekha, B Agerberth… - Frontiers in …, 2020 - frontiersin.org
… peptides (AMPs), reactive oxygen species (ROS and NO) and … Candida albicans by commensal
bacteria, where cathelicidin … Commensal Clostridia species can modulate retinoic acid …

New insights into the interplay between autophagy, gut microbiota and inflammatory responses in IBD

A Larabi, N Barnich, HTT Nguyen - Autophagy, 2020 - Taylor & Francis
… in response to commensal bacteria leads to recruitment of … reactive oxygen species (ROS)
[Citation41] ( Figure 1C ). … IL22 signaling in the intestinal epithelium via modulating CGAS (…

Microbial adaptation to the healthy and inflamed gut environments

Y Guo, S Kitamoto, N Kamada - Gut Microbes, 2020 - Taylor & Francis
… coli (AIEC) modulate the expression of virulence and … inflammation induces reactive oxygen
species (ROS) and nitric … -depleting agents and reactive oxygen and nitrogen species. This …

… Lactobacillus plantarum JBC5 improves longevity and healthy aging by modulating antioxidative, innate immunity and serotonin-signaling pathways in Caenorhabditis …

A Kumar, T Joishy, S Das, MC Kalita, AK Mukherjee… - Antioxidants, 2022 - mdpi.com
… of reactive oxygen species and improved mitochondrial function, thereby reducing apoptosis
in worms. The capability of a single bacterium … for promotion as a next-generation probiotic. …

Understanding the Dynamics of Human Defensin Antimicrobial Peptides: Pathogen Resistance and Commensal Induction

V Kumaresan, Y Kamaraj, S Subramaniyan… - Applied Biochemistry …, 2024 - Springer
… However, numerous non-pathogenic commensal bacteria … the induction of HD by commensal
organisms remains to be fully … plays a crucial part in modulating the host’s responses to …

Pleiotropic signaling by reactive oxygen species concerted with dietary phytochemicals and microbial-derived metabolites as potent therapeutic regulators of the …

T Murai, S Matsuda - Antioxidants, 2023 - mdpi.com
… in basic physiological functions, future therapeutics should be designed to modulate the …
Commensal bacteria in the intestinal mucus layer produce a variety of metabolites through

Limiting oxidative DNA damage reduces microbe-induced colitis-associated colorectal cancer

T Irrazabal, BK Thakur, M Kang, Y Malaise… - Nature …, 2020 - nature.com
… Factors that might directly mediate genetic damage in the inflammatory milieu include
reactive oxygen species (ROS) and reactive nitrogen intermediates (RNI) produced by activated …

Perturbed mitochondrial dynamics, an emerging aspect of epithelial-microbe interactions

DM McKay, NL Mancini, J Shearer… - American Journal of …, 2020 - journals.physiology.org
… Furthermore, reactive oxygen species (ROS) generated as a … protein, may be the cells’
original signaling molecules (33). Thus, … for commensal bacteria-derived molecules to modulate