Environmental distribution, metabolic fate, and degradation mechanism of chlorpyrifos: recent and future perspectives

RS Bhende, U Jhariya, S Srivastava… - Applied Biochemistry …, 2022 - Springer
… CP and its derivatives can affect the biological activities of … leads to the generation of
chlorpyrifos-oxon, an unstable metabolite … Furthermore, a comparative structural and biochemical …

Recent advances in assessment methods and mechanism of microbe-mediated chlorpyrifos remediation

A Raj, A Kumar - Environmental Research, 2022 - Elsevier
… and chlorpyrifos oxon are more lethal than the parent chlorpyrifos … of chlorpyrifos vary
depending on numerous parameters of soil … TCP shows antimicrobial activity, thus inhibiting the …

Insight into the environmental fate, hazard, detection, and sustainable degradation technologies of chlorpyrifos—an organophosphorus pesticide

P Kumar, M Arshad, A Gacem, S Soni, S Singh… - … Science and Pollution …, 2023 - Springer
… develop CPY remediation approaches and its derivatives from the environment. Currently, …
CPY Oxon, one of its principal metabolites, is a member of the aryl phosphorothioate family …

Chlorpyrifos occurrence and toxicological risk assessment: a review

E Wołejko, B Łozowicka, A Jabłońska-Trypuć… - International journal of …, 2022 - mdpi.com
Chlorpyrifos-oxon (CPF-ox) and 3,5,6-TCP have high toxicity to microbial populations and soil
enzymatic activity [… high concentrations of CPF and its derivatives can cause acute lethality …

Microbial degradation of organophosphorus pesticides using whole cells and enzyme extracts

JY Santillan, A Muzlera, M Molina, ES Lewkowicz… - Biodegradation, 2020 - Springer
… higher hydrolytic activities than for the other oxon derivatives. … that chlorpyrifos is a
thiophosphotriester derivative and, as … ), probably due to its low solubility in comparison to other …

Effects of chlorpyrifos on the metabolic profiling of Bacillus megaterium strain RRB

M Zhang, Y Li, F Feng, X Yu, J Ge, Y Zhang, J Nie - Chemosphere, 2022 - Elsevier
chlorpyrifos and its degradation products (chlorpyrifos-oxon, … that of chlorpyrifos-oxon (0.048
μg/L) and chlorpyrifos-methyl (… of TCP and chlorpyrifos-oxon in bacterial samples appeared …

Strategies in microbial degradation enhancement of chlorpyrifos–a review based on the primary approaches in soil bioremediation

EM Varghese, AP, J MS - Biocatalysis and Biotransformation, 2022 - Taylor & Francis
… and for chlorpyrifos oxon, a major chlorpyrifos degradation by-… These toxic chlorpyrifos
derivatives should be eliminated to … in improving the soil fertility and microbial activity favourable …

Complementary biological and computational approaches identify distinct mechanisms of chlorpyrifos versus chlorpyrifos-oxon-induced dopaminergic neurotoxicity

SR Sammi, T Syeda, KD Conrow… - Toxicological …, 2023 - academic.oup.com
… neurons (showing high oxon potency in comparison to CPF) (B… Comparison of effect of
CPF-oxon versus CPF treatment on DA-dependent behavior (F). A 2-day treatment with CPF-oxon

Chlorpyrifos Toxicity in Fishes: A Perspective

R Akhtar, AF Wali, S Shakeel, S Rasool… - … Pollution and Aquatic …, 2021 - taylorfrancis.com
… Nonenzymatic functions of acetylcholinesterase splice variants in the developmental
neurotoxicity of organophosphates: Chlorpyrifos, chlorpyrifos oxon, and diazinon. Environ. Health …

The growing concern of chlorpyrifos exposures on human and environmental health

NK Nandi, A Vyas, MJ Akhtar, B Kumar - Pesticide biochemistry and …, 2022 - Elsevier
… highly electrophilic intermediates are principal toxic metabolites. The active form of CP ie
chlorpyrifos oxon (CP-oxon) is responsible for both the insecticidal activity and is also of …