[HTML][HTML] Patient-reported outcomes from FLAURA: osimertinib versus erlotinib or gefitinib in patients with EGFR-mutated advanced non-small-cell lung cancer

NB Leighl, N Karaseva, K Nakagawa, BC Cho… - European Journal of …, 2020 - Elsevier
erlotinib/gefitinib arm in the current analysis but did not change from baseline in the osimertinib
arm, which may reflect differences in CNS progression between the two treatment arms. …

Clinical outcomes of gefitinib and erlotinib in patients with NSCLC harboring uncommon EGFR mutations: A pooled analysis of 438 patients

C Wang, K Zhao, S Hu, W Dong, Y Gong, M Li, C Xie - Lung Cancer, 2022 - Elsevier
… investigate the outcomes of gefitinib and erlotinib in patients with non-small cell lung
cancer … of this study design, it is not possible to directly compare the outcomes of the first-generation …

[HTML][HTML] … central nervous system efficacy among gefitinib, erlotinib and afatinib in patients with epidermal growth factor receptor mutation-positive non-small cell lung …

HA Jung, SY Woo, SH Lee, JS Ahn… - Translational Lung …, 2020 - ncbi.nlm.nih.gov
… 17.3 months for gefitinib, 12.4 months for erlotinib, and 23.3 … % CI, 0.47–0.83) compared
with gefitinib or erlotinib. In the … CNS failure compared with gefitinib or erlotinib after adjusting …

[HTML][HTML] … Difference in Clinical Outcomes Between Osimertinib and Afatinib for First-Line Treatment in Patients with Advanced and Recurrent EGFR-Mutant Non-Small …

YH Huang, KH Hsu, JS Tseng, TY Yang, KC Chen… - Targeted Oncology, 2022 - Springer
… of TKI treatment between afatinib and osimertinib [16, 17]. However, the median follow-up
time was not … Thus, we conducted the present study in order to compare the clinical outcomes

[HTML][HTML] … outcomes of first-generation and second-generation epidermal growth factor receptor tyrosine kinase inhibitors in a large cohort of European non-small-cell …

A Pluzanski, M Krzakowski, D Kowalski… - ESMO open, 2020 - Elsevier
… Our results show better 1-year OS rate with afatinib than gefitinib but not erlotinib. We did …
Regarding this finding we did not performed comparative analysis between our results and …

Survival benefits from afatinib compared with gefitinib and erlotinib among patients with common EGFR mutation in first‐line setting

WC Kwok, JCM Ho, TCC Tam, MSM Ip… - Thoracic …, 2022 - Wiley Online Library
… ) are recommended as first-line treatment in non-small cell lung cancer (NSCLC) patients with
comparisons between regimens with first-line use of afatinib, gefitinib or erlotinib, followed

[HTML][HTML] Comparing gefitinib and traditional chemotherapy for better survival in patients with non-small cell lung cancer: A systematic review

S Kanagalingam, ZU Haq, NV Srinivasan, AI Khan… - Cureus, 2023 - ncbi.nlm.nih.gov
… to be treated as a chronic disease [10]. In this systematic review, we will compare the use of
gefitinib as an alternative treatment in NSCLC and compare it to traditional chemotherapies. …

[HTML][HTML] The impact of different first-line EGFR-TKIs on the clinical outcome of sequential osimertinib treatment in advanced NSCLC with secondary T790M

YH Huang, JS Tseng, KH Hsu, KC Chen, KY Su… - Scientific Reports, 2021 - nature.com
… )s to the clinical efficacy of osimertinib in EGFR-mutant non-small-cell lung cancer (NSCLC) …
have on the clinical outcome of sequential osimertinib treatment. Compared with other real-…

[HTML][HTML] … overall survival in a randomized study comparing dacomitinib with gefitinib as first-line treatment in patients with advanced non-small-cell lung cancer and …

TS Mok, Y Cheng, X Zhou, KH Lee, K Nakagawa… - Drugs, 2021 - Springer
… In conclusion, the OS benefit from first-line treatment with dacomitinib versus gefitinib
was maintained after extended follow-up in patients with advanced NSCLC with EGFR-activating …

Genomic alterations and clinical outcomes in patients with lung adenocarcinoma with transformation to small cell lung cancer after treatment with EGFR tyrosine …

W Wang, C Xu, H Chen, J Jia, L Wang, H Feng… - Lung Cancer, 2021 - Elsevier
clinical outcomes, we demonstrated that anlotinib might be a favorable regimen for use
after … However, our results showed that there was no difference in sex and smoking status. …