Cost-effectiveness analysis of tyrosine kinase inhibitors (erlotinib vs. gefitinib vs. afatinib) in non-small-cell lung cancer

F Nurhayati, Y Anggriani, E Syahruddin… - Journal of Applied …, 2021 - japsonline.com
compare the effectiveness and costs of using erlotinib, gefitinib, or afatinib in the treatment of
NSCLC. … was more effective at increasing PFS compared to erlotinib and afatinib. The cost-…

[HTML][HTML] … different central nervous system efficacy among gefitinib, erlotinib and afatinib in patients with epidermal growth factor receptor mutation-positive non-small …

HA Jung, SY Woo, SH Lee, JS Ahn… - Translational Lung …, 2020 - ncbi.nlm.nih.gov
gefitinib or erlotinib (12). Although afatinib has superior efficacy for brain metastasis compared
… (13), its efficacy for CNS metastasis has not been fully compared with other EGFR TKIs. In …

[HTML][HTML] Effectiveness and safety of afatinib, gefitinib, and erlotinib for treatment-naïve elderly patients with epidermal growth factor receptor-mutated advanced non …

LJ Hung, PC Hsu, CT Yang, CHS Kuo… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
… describe the effectiveness and safety of afatinib, gefitinib, and erlotinib for elderly … afatinib
required dose reductions or discontinuation compared to those treated with gefitinib or erlotinib

Cost-effectiveness analysis of afatinib, erlotinib, and gefitinib as first-line treatments for EGFR mutation-positive non-small-cell lung cancer in Ontario, Canada

YJ Kim, M Oremus, HH Chen, T McFarlane… - …, 2021 - Springer
… The objective of this study was to compare the cost effectiveness of first-line epidermal
growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) for the treatment of non-small-cell …

Cost-effectiveness analysis of tyrosine kinase inhibitors (erlotinib, gefitinib, afatinib and osimertinib) as first-line therapy for epidermal growth factor receptor-mutated …

S Luo, L Dong, Y Li, D Xu… - Journal of Chinese …, 2021 - search.ebscohost.com
… studies have compared the cost-effectiveness of these four … the cost-effectiveness of erlotinib,
gefitinib, afatinib and osimertinib … A Markov model was constructed to compare the 10-year …

Efficacy and dose of afatinib in patients with nonsmall cell lung cancer after failure of prior gefitinib or erlotinib treatment

H Choi, JK Lee, HJ Oh, MS Kim, BG Kho… - Thoracic …, 2021 - Wiley Online Library
… NSCLC who progressed after prior treatment with erlotinib or gefitinib, which is similar …
afatinib because of AEs, there was no significant difference in the discontinuation rate compared

[HTML][HTML] Cost-effectiveness analysis of first and second-generation EGFR tyrosine kinase inhibitors as first line of treatment for patients with NSCLC harboring EGFR …

O Arrieta, R Catalán, S Guzmán-Vazquez, F Barrón… - BMC cancer, 2020 - Springer
… the cornerstone treatment of patients with non-small cell lung … study was to compare the
cost-effectiveness of three different … cost-effectiveness analysis determined that afatinib was a …

Real-life effectiveness of afatinib versus gefitinib in patients with non-small-cell lung cancer: a Czech multicentre study

M Svaton, M Bratová, O Fischer, J Krejci… - Anticancer …, 2021 - ar.iiarjournals.org
… Background/Aim: We investigated efficacy differences for afatinib versus gefitinib in non-small-…
trials showed no significant differences in efficacy between afatinib gefitinib, erlotinib, and …

[HTML][HTML] Overall survival of patients with EGFR mutation-positive non-small-cell lung cancer treated with erlotinib, gefitinib or afatinib under drug programmes in …

M Brzozowska, W Wierzba… - Archives of Medical …, 2021 - ncbi.nlm.nih.gov
… from differences in the frequency of mutation types in the populations concerned, especially
considering that most studies assessing the effectiveness of gefitinib and erlotinib were …

Comparison of afatinib and erlotinib combined with bevacizumab in untreated stage IIIB/IV epidermal growth factor receptor-mutated lung adenocarcinoma patients: a …

SH Lee, YC Lin, LC Chiu, JS Ju… - Therapeutic …, 2022 - journals.sagepub.com
… Although bevacizumab in combination with afatinib or erlotinib is an effective and … non-small-cell
lung cancer (NSCLC), there are very few clinical data comparing afatinib and erlotinib