Efficacy of voriconazole against Aspergillus fumigatus infection depends on host immune function

EE Rosowski, J He, J Huisken, NP Keller… - Antimicrobial agents …, 2020 - Am Soc Microbiol
… For comparison, voriconazole is estimated to have an MIC in the range of 0.25 to 1 μg/ml
in vitro against a variety of A. fumigatus isolates, including the strain used here, Af293 (21…

Azole antifungals and inter-individual differences in drug metabolism: the role of pharmacogenomics and precision medicine

M Biswas, J Shobana, P Jinda… - Expert Opinion on Drug …, 2023 - Taylor & Francis
… Antifungal activities of posaconazole, ravuconazole, and voriconazole compared to those
of itraconazole and amphotericin B against 239 clinical isolates of aspergillus spp. and other …

Susceptibility of Filamentous Fungi to Voriconazole in Malaysia Tested by Sensititre YeastOne and CLSI Microdilution Methods

XT Tan, SJ Ginsapu, F binti Amran, S binti Shukor - 2021 - researchsquare.com
Aspergillus infection [8, 19]. The survival was proved greater with voriconazole treatment
compared to itraconazole treatment [9]… In vitro studies of activity of voriconazole (UK-109,496), a …

Beyond ergosterol: Strategies for combatting antifungal resistance in Aspergillus fumigatus and Candida auris

R Cruz, WM Wuest - Tetrahedron, 2023 - Elsevier
… Synergy with the azole antifungals fluconazole and itraconazole was observed across a …
albicans was significantly more resistant to poacic acid treatment compared to S. cerevisiae, …

Therapeutic drug monitoring of antifungal agents in critically ill patients: is there a need for dose optimisation?

D Baracaldo-Santamaría, JD Cala-Garcia… - Antibiotics, 2022 - mdpi.com
… using itraconazole, posaconazole or voriconazole as antifungal … as the initial treatment for
invasive aspergillosis [33]. … patients treated with anidulafungin had lower AUC 0–24 compared

Fusarium Keratitis—Review of Current Treatment Possibilities

M Szaliński, A Zgryźniak, I Rubisz, M Gajdzis… - Journal of Clinical …, 2021 - mdpi.com
… than Aspergillus cases. At the same time, ulcers caused by … significant clinical differences,
comparisons between NAT … , the addition of oral voriconazole may be considered in severe …

[HTML][HTML] Non-Aspergillus mould lung infections

P Puerta-Alcalde, C Garcia-Vidal - European Respiratory …, 2022 - Eur Respiratory Soc
… of echinocandins and triazoles, and voriconazole or itraconazole and terbinafine [106–108]. …
terms of mortality when comparing the combination of voriconazole and terbinafine against …

Debilitating limb pain and weakness as complications of long‐term voriconazole therapy.

T Harding, C Harris, J Smart… - Journal of Paediatrics & …, 2021 - search.ebscohost.com
… resistant (fluconazole, itraconazole and posaconazole) for … Aspergillus fumigatus4 as
occurred in our patient who was … risk of hepatotoxicity with voriconazole compared to other anti-…

[HTML][HTML] Aspergillus Endocarditis

K Gopal, PN Bhaskaran, M Moni, N Shashindran - Indian Heart Journal, 2024 - Elsevier
… In general, as in other forms of invasive aspergillosis, voriconazole is preferred as the first …
azole based medical therapy had a much better outcome compared to medical therapy alone. …

Fungal genomics in respiratory medicine: what, how and when?

AP Brackin, SJ Hemmings, MC Fisher, J Rhodes - Mycopathologia, 2021 - Springer
… pathogen Aspergillus fumigatus and primarily treated using … of aspergillosis have a higher
risk of mortality when compared … a range of azoles including voriconazole, itraconazole, and …