Complement, inflammation and thrombosis
E Rawish, M Sauter, R Sauter… - British Journal of …, 2021 - Wiley Online Library
… both thrombosis and complement … Complement-mediated thrombosis and its relevance
for disease. The interplay between complement activation and platelet-mediated thrombosis …
for disease. The interplay between complement activation and platelet-mediated thrombosis …
[HTML][HTML] Interplay between inflammation and thrombosis in cardiovascular pathology
K Stark, S Massberg - Nature Reviews Cardiology, 2021 - nature.com
… Conversely, platelets also provide a surface for complement activation in infectious diseases
and platelet-bound complement boosts the inflammatory functions of innate immune cells …
and platelet-bound complement boosts the inflammatory functions of innate immune cells …
[HTML][HTML] COVID‐19: a collision of complement, coagulation and inflammatory pathways
AJ Chauhan, LJ Wiffen, TP Brown - Journal of Thrombosis and …, 2020 - Elsevier
… Increased complement activation has been implicated in thrombotic microangiopathy,
systemic inflammation, and hypercoagulation in rare disorders and pathogenic virus infections, …
systemic inflammation, and hypercoagulation in rare disorders and pathogenic virus infections, …
[HTML][HTML] It takes two to thrombosis: hemolysis and complement
L Delvasto-Nuñez, I Jongerius, S Zeerleder - Blood reviews, 2021 - Elsevier
… the role of complement activation and hemolysis in the onset of thrombosis in hemolytic
diseases. … activation contributing to the pathogenesis of thrombosis. Finally, we will combine this …
diseases. … activation contributing to the pathogenesis of thrombosis. Finally, we will combine this …
[HTML][HTML] Complement in hemolysis-and thrombosis-related diseases
… Cross-interplay of the complement and hemostatic systems could … -inflammation” (67).
Abundant evidence demonstrated that complement hyperactivation is correlated with thrombosis …
Abundant evidence demonstrated that complement hyperactivation is correlated with thrombosis …
[HTML][HTML] Crosstalk between the renin–angiotensin, complement and kallikrein–kinin systems in inflammation
Z Bekassy, I Lopatko Fagerström, M Bader… - Nature Reviews …, 2022 - nature.com
… For a more comprehensive overview of the complement system, the reader is referred to ref.
… of the complement system that are important for inflammation and coagulation or thrombosis …
… of the complement system that are important for inflammation and coagulation or thrombosis …
Inflammation, infection and venous thromboembolism
ME Colling, BE Tourdot, Y Kanthi - Circulation research, 2021 - Am Heart Assoc
… a central regulator of inflammation and thrombosis, pre-formed TF can rapidly shift
functions from cell signaling to coagulation by conformational activation in a complement-dependent, …
functions from cell signaling to coagulation by conformational activation in a complement-dependent, …
Inflammation and thrombosis in COVID-19 pathophysiology: proteinase-activated and purinergic receptors as drivers and candidate therapeutic targets
K Sriram, PA Insel - Physiological reviews, 2021 - journals.physiology.org
… on inflammatory and other cells promotes complement activation … complement component
occurs and increases with tissue injury and inflammation by properdin and other inflammatory …
occurs and increases with tissue injury and inflammation by properdin and other inflammatory …
Will complement inhibition be the new target in treating COVID-19–related systemic thrombosis?
CM Campbell, R Kahwash - Circulation, 2020 - Am Heart Assoc
… Coronavirus and complement.A, Simplified diagram of the common complement pathway.
Eculizumab … B, In humans, overactivation of the complement pathway can lead to thrombotic …
Eculizumab … B, In humans, overactivation of the complement pathway can lead to thrombotic …
The case of complement activation in COVID-19 multiorgan impact
… In this review, we discuss the relative role of the different complement activation … inflammation
and thrombosis and propose the hypothesis that blockade of the terminal complement …
and thrombosis and propose the hypothesis that blockade of the terminal complement …