[HTML][HTML] Platelets as mediators of neuroinflammation and thrombosis
… thrombosis and inflammation, … inflammatory and thrombotic responses, which has recently
been reviewed elsewhere (38). Moreover, a crosstalk between platelets and the complement …
been reviewed elsewhere (38). Moreover, a crosstalk between platelets and the complement …
[HTML][HTML] Thrombo-inflammation in cardiovascular disease: an expert consensus document from the Third Maastricht Consensus Conference on Thrombosis
E d'Alessandro, C Becker, W Bergmeier… - Thrombosis and …, 2020 - thieme-connect.com
Thrombo-inflammation describes the complex interplay between blood coagulation and
inflammation that plays a critical role in cardiovascular diseases. The third Maastricht …
inflammation that plays a critical role in cardiovascular diseases. The third Maastricht …
Analysis of complement deposition and viral RNA in placentas of COVID-19 patients
JJ Mulvey, CM Magro, LX Ma, GJ Nuovo… - Annals of diagnostic …, 2020 - Elsevier
… Vascular complement deposition in the … thrombosis without complement deposition may
reflect the systemic nature of COVID-19's procoagulant effects unrelated to systemic complement …
reflect the systemic nature of COVID-19's procoagulant effects unrelated to systemic complement …
[HTML][HTML] Platelet FcγRIIA in immunity and thrombosis: adaptive immunothrombosis
P Patel, JV Michael, UP Naik, SE McKenzie - Journal of Thrombosis and …, 2021 - Elsevier
… immune response induced by the formation of thrombi inside blood vessels, in … thrombotic
disorders. By virtue of their receptors for various classes of immunoglobulins and complement …
disorders. By virtue of their receptors for various classes of immunoglobulins and complement …
The emerging threat of (micro) thrombosis in COVID-19 and its therapeutic implications
JD McFadyen, H Stevens, K Peter - Circulation research, 2020 - Am Heart Assoc
… complement activation and the production of inflammatory … thrombus formation in animal
models of thrombosis without … animal models of systemic inflammatory response syndrome, …
models of thrombosis without … animal models of systemic inflammatory response syndrome, …
Thrombosis in COVID‐19
… Complement activation is robust in sepsis, and inhibition of the complement system can …
microvascular injury accompanied by terminal components of complement activation: C5b-9, …
microvascular injury accompanied by terminal components of complement activation: C5b-9, …
Microvascular thrombosis: experimental and clinical implications
MA Bray, SE Sartain, J Gollamudi, RE Rumbaut - Translational Research, 2020 - Elsevier
… these enzymes in regulation of thrombotic tone in endothelial cells: endothelial cell COX-1
and COX-2 both prevent thrombosis, albeit via distinct and complementary pathways. From a …
and COX-2 both prevent thrombosis, albeit via distinct and complementary pathways. From a …
Neurovascular injury with complement activation and inflammation in COVID-19
The underlying mechanisms by which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
leads to acute and long-term neurological manifestations remains obscure. We …
leads to acute and long-term neurological manifestations remains obscure. We …
Severe COVID‐19 infection and thrombotic microangiopathy: success does not come easily.
E Gavriilaki, RA Brodsky - British journal of haematology, 2020 - search.ebscohost.com
… hit are pregnancy, inflammation, surgery or autoimmunity.The complement system is part of
the … Except for inflammation, a link also exists between the complement system and platelet …
the … Except for inflammation, a link also exists between the complement system and platelet …
Pharmacological approach for the reduction of inflammatory and prothrombotic hyperactive state in COVID-19 positive patients by acting on complement cascade
A Vitiello, R La Porta, V D'Aiuto, F Ferrara - Human Immunology, 2021 - Elsevier
… terminal complement pathway blockade represents a potential therapeutic option to reduce
the inflammatory state and the risk of thrombosis … with unregulated complement proteins and …
the inflammatory state and the risk of thrombosis … with unregulated complement proteins and …