[HTML][HTML] The role of long non-coding RNAs in the tumor immune microenvironment

Y Guo, Y Xie, Y Luo - Frontiers in Immunology, 2022 - frontiersin.org
… post-transcriptional mRNA functions by complementary base … The differentiation of Th cells
can be regulated by lncRNAs. … medium to large B lymphoid cells. LncRNAs were reported to …

[图书][B] Mutations in IKAROS Lead to an Altered Epigenetic and Chromatin Landscape Contributing to the Manifestation of B-Cell Related Disorders

PDR Ramirez - 2021 - search.proquest.com
… subsequent differentiation towards … regulate gene expression either directly or through the
recruitment of chromatin remodeling complexes. The epigenetic gene regulatory mechanisms, …

Whole-transcriptome profiling and circRNA-miRNA-mRNA regulatory networks in B-cell development

J Pan, S Hu, X Ren, H Hu, X Deng, B Yu… - Frontiers in …, 2022 - frontiersin.org
… -467e-5p, which competes against their target complement receptor 2 (Cr2/CD21) (Figure
9B)… ceRNAs to regulate miRNA-targeted mRNA during B-cell differentiation and development, …

The functions of EZH2 in immune cells: Principles for novel immunotherapies

FF Shao, BJ Chen, GQ Wu - Journal of Leukocyte Biology, 2021 - academic.oup.com
… via antibody-dependent cellular cytotoxicity or complement-dependent cytotoxicity 110 ; (ii) …
PC differentiation. EZH2 deletion in B cells has also been reported to impair B lymphoid cell …

An integrative model of pathway convergence in genetically heterogeneous blast crisis chronic myeloid leukemia

…, CC Khor, CTJ Ong, WJW Soon… - Blood, The Journal …, 2020 - ashpublications.org
… key genes involved in myeloid differentiation and tumor suppressor function via so-called
epigenetic switching, whereas PRC1 represses an overlapping and distinct set of genes, …

Redefining the biological basis of lineage-ambiguous leukemia through genomics: BCL11B deregulation in acute leukemias of ambiguous lineage

LE Montefiori, CG Mullighan - Best Practice & Research Clinical …, 2021 - Elsevier
… genomic sequencing and complementary approaches have … a myeloid and T- or B-lymphoid
immunophenotype or, more … upregulate T cell differentiation gene expression programs in …

The role of epigenetic modifications for the pathogenesis of Crohn's disease

M Hornschuh, E Wirthgen, M Wolfien, KP Singh… - … epigenetics, 2021 - Springer
… the TXK gene for regulation of the adaptive immune response, function, and differentiation of
… SPI1 is responsible for developing myeloid and B-lymphoid cells [105], whereas RPS6KA2 …

Multi-lineage Differentiation from Hematopoietic Stem Cells

X Wang, S Liu, J Yu - Hematopoietic Stem Cells: Keystone of Tissue …, 2024 - Springer
… Commitment to differentiation progressively … gene expression. In this review, we will
summarize the current understanding of the molecular mechanisms underlying HSC differentiation

The transcription factors GFI1 and GFI1B as modulators of the innate and acquired immune response

J Fraszczak, T Möröy - Advances in immunology, 2021 - Elsevier
… and differentiationearly lymphoid differentiation or by T and B cell receptors during activation
of lymphoid cells. Myeloid cells also depend on GFI1 at both stages of early differentiation

[HTML][HTML] Angioimmunoblastic T-cell lymphoma and correlated neoplasms with T-cell follicular helper phenotype: from molecular mechanisms to therapeutic advances

LAPC Lage, HF Culler, CO Reichert… - Frontiers in …, 2023 - frontiersin.org
… with epigenetic regulation, leading to differentiation and … (ISH) for EBV and complementary
molecular tests, such as T-… involving the RhoA gene and other epigenetic regulators by …