Synthetic carbohydrate chemistry and translational medicine

SS Shivatare, CH Wong - The Journal of organic chemistry, 2020 - ACS Publications
… or synthesis are often required for glycobiology studies. … and enzymatic synthesis of complex
carbohydrates, glycan … through mild periodate or enzyme-based oxidation of polyhydroxyls …

Strategies for automated enzymatic glycan synthesis (AEGS)

KP Hussnaetter, P Palm, A Pich, M Franzreb… - Biotechnology …, 2023 - Elsevier
… of enzymatic glycan synthesis in an automated system has high demands on the equipment,
… For the enzymatic synthesis of glycans, three classes of carbohydrate-active enzymes (CAZy…

Biocatalyzed synthesis of glycostructures with anti-infective activity

P Hoyos, A Perona, T Bavaro, F Berini… - Accounts of Chemical …, 2022 - ACS Publications
… In glycochemistry and glycobiology, enzymes belonging to the … Enzyme-based procedures
might be highly efficient and … and synthetic chemistry methods are expanding our tools to …

[HTML][HTML] Cell-based high-throughput screening of polysaccharide biosynthesis hosts

ZX Liu, SL Huang, J Hou, XP Guo, FS Wang… - Microbial Cell …, 2021 - Springer
… These enzymes and their mutants are in high demand as tool catalysts for synthesis of …
synthesis. With the rapid development of glycobiology and glycoengineering, carbohydrates have …

[图书][B] Automated Solution-Phase Synthesis of Thioglycoside Analogues and Efforts toward a Convergent Synthesis of Xyloglucan Fragments

MK Kern - 2022 - search.proquest.com
… 1).3, 4 Thus, carbohydrates are fundamental to the field of glycobiology, as well as human …
Synthesis of complex carbohydrates and glycoconjugates: Enzyme-based and programmable

Biocatalyzed Synthesis of Glycostructures with Anti-infective Activity

P Hoyos Vidal, A Perona Requena, T Bavaro, F Berini… - 2022 - docta.ucm.es
… In glycochemistry and glycobiology, enzymes belonging to the … Enzyme-based procedures
might be highly efficient and … and synthetic chemistry methods are expanding our tools to …

[HTML][HTML] More small tools for sweet challenges: advances in microfluidic technologies for glycan analysis

F Pinnock, JD Carten, S Daniel - Frontiers in Lab on a Chip …, 2024 - frontiersin.org
… field of glycobiology, we provide a brief overview of traditional approaches to carbohydrate
… microfluidics make them robust tools for analyzing complex carbohydrates. An obvious merit …

[HTML][HTML] Advances in glycoside and oligosaccharide synthesis

CJ Crawford, PH Seeberger - Chemical Society Reviews, 2023 - pubs.rsc.org
… clear, as the field of glycobiology continues to develop. The … Enzyme-based approaches exist
and can be used in … for the ‘programmable’ one-pot synthesis of complex oligosaccharides. …

[HTML][HTML] Synthesis of glycoconjugates utilizing the regioselectivity of a lytic polysaccharide monooxygenase

B Westereng, SK Kračun, S Leivers, MØ Arntzen… - Scientific reports, 2020 - nature.com
… specific carbohydrates by microbes 37 . The labeling strategy presented here provides new
tools … Chemo-enzymatic protocols enable synthesis of glycoconjugates with unprecedented …

A study of the practicality of cell-free protein synthesis for the commercial manufacture of monoclonal antibodies

M O'Halloran - 2022 - dspace-test.interleaf.ie
… , as well as recent developments in glycobiology. The most complex post-translation modification
is … There are advantages in smallmolecule-based systems compared to enzyme-based