… In this study, genome-wide transcriptome heterogeneity of seven PLCs was analyzed …
comparison from normal to leading-edge to tumor regions, we found that the tumor capsule …

Summary A better understanding of transcriptional evolution of IDH-wild-type glioblastoma
may be crucial for treatment optimization. Here, we perform RNA sequencing (RNA-seq) (n = …

… to profile the transcriptomes of individual cells from dissociated primary tumors or metastatic
biopsies obtained from patients with PDAC. Unsupervised clustering analysis as well as a …

… as EGFR and MYC and tumor suppressors such as TP63 and NOTCH3 further contribute
to the disease progression 5,6 . Previous transcriptome analyses have revealed thousands of …

… transcriptomes of 158,577 cells from 11 patients’ paratumors, localized/advanced tumors, …
distant metastases, covering comprehensive clinical courses of PTC. Our data identifies a “…

… Here, we perform scRNA-Seq to analyze the microenvironment from tumor and adjacent
nonmalignant esophageal tissues from 11 ESCC patients. We reveal profound cellular …

… predictive effect of gut microbiota on tumor progression and recurrence/metastasis. By the
simultaneous integrated analysis of the liver tumor transcriptome, gut microbiome, and clinical …

… We used single-cell transcriptome sequencing and multiplex immunohistochemistry to
investigate the immune microenvironment of EGFR-mutant and EGFR wild-type LUADs and …

… cancer specimens To examine whether aberrant splicing isoforms also exist in cancer cells
in vivo, we next analyzed clinical lung cancer … for the cell line analysis of clinical samples (…

… cancer risk loci and possible causal genes, we performed a pancreatic cancer transcriptome-…
, MetaXcan, and Summary-MulTiXcan. We integrated genome-wide association studies …