[HTML][HTML] Molecular characterization of squamous cell carcinoma of the anal canal

SA Armstrong, R Malley, H Wang, HJ Lenz… - Journal of …, 2021 - ncbi.nlm.nih.gov
… TP53-MT tumors, and differences between local and metastatic tumors. SCCA specimens
(n=… an extensive comprehensive genomic profiling with NGS and gene expression profiling for …

Advanced squamous cell carcinomas of the pelvic and perineal region: a comprehensive genomic profiling study

A Necchi, PE Spiess, M Bandini, G Basile… - The …, 2022 - academic.oup.com
… from phase III trials testing anti-programmed cell-death-1/ligand-… for patients with
recurrent/metastatic HNSCC irrespective of PD-… , or metastatic cervical carcinoma, including cases …

[HTML][HTML] The first comprehensive genomic characterization of rectal squamous cell carcinoma

C Astaras, C De Vito, P Chaskar, A Bornand… - Journal of …, 2023 - Springer
complete molecular characterization of this tumoral entity. In this context, we used genomic
profile … literature for aSCC in pre- and post-CRT for local and metastatic disease [25, 27, 28]. …

[HTML][HTML] Comparison of clinicopathological and genomic profiles in anal squamous cell carcinoma between Japanese and Caucasian cohorts

T Ito, D Takayanagi, S Sekine, T Hashimoto… - Scientific reports, 2023 - nature.com
… The global standard treatment for advanced ASCC without distant metastasis is concurrent
… As reported in these clinical trials, the outcome of ASCC without distant metastatic lesions …

[HTML][HTML] Comprehensive characterization of the mutational landscape in localized anal squamous cell carcinoma

L Trilla-Fuertes, I Ghanem, J Maurel, G Laura… - Translational …, 2020 - Elsevier
Anal squamous cell carcinoma (ASCC) is a rare neoplasm. Chemoradiotherapy is the
standard of care, with no therapeutic advances achieved over the past three decades. Thus, a …

[HTML][HTML] Genetic profile and functional proteomics of anal squamous cell carcinoma: proposal for a molecular classification

L Trilla-Fuertes, I Ghanem, A Gamez-Pozo… - Molecular & Cellular …, 2020 - ASBMB
Comprehensive genomic profiling of anal squamous cell carcinoma reveals distinct … for
this malignancy and present with no metastasis. Demographic information related to the …

[HTML][HTML] A clinical and molecular portrait of non-metastatic anal squamous cell carcinoma

S Iseas, M Golubicki, J Robbio, G Ruiz, F Guerra… - Translational …, 2021 - Elsevier
Anal squamous cell carcinoma (ASCC) is a rare … Despite improved outcomes in non-metastatic
ASCC, definitive … of 79 non-metastatic ASCC patients with complete definitive …

[HTML][HTML] Extensive molecular profiling of squamous cell anal carcinoma in a phase 2 trial population: translational analyses of the “CARACAS” study

AA Prete, P Manca, M Messina, V Formica… - … Journal of Cancer, 2023 - Elsevier
… burden (TMB) and comprehensive genomic profiling by FoundationOne CDx. Tumour-…
metastatic sites, also because the number of metastatic samples was limited in this study. …

[HTML][HTML] Genome-wide host methylation profiling of anal and cervical carcinoma

EM Siegel, A Ajidahun, A Berglund, W Guerrero… - PloS one, 2021 - journals.plos.org
… In this study, exclusively using genome-wide methylation analyses, we sought to identify
comprehensive methylomic profiles that differentiated anal or cervical cancer from normal …

[HTML][HTML] … with chemotherapy followed by concurrent immunoradiotherapy in locally advanced anal canal squamous cell carcinoma patients: antitumor efficacy, safety …

WW Xiao, Y Yuan, SH Wang, Z Liao, PQ Cai… - Frontiers in …, 2022 - frontiersin.org
… the treatment of metastatic anal squamous cell carcinoma (9)… locoregional disease of anal
squamous cell carcinoma is still … have provided a comprehensive genomic profile of ACSCC. …