Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis
… EBV EBNA3A phenocopies EBF1 activities in LMP1-expressing B cells, … CD40 receptor
to mainly induce NF-κB and JNK signaling pathways (5, 6). LMP2A resembles a constitutively …
to mainly induce NF-κB and JNK signaling pathways (5, 6). LMP2A resembles a constitutively …
Epstein-Barr virus induces germinal center light zone chromatin architecture and promotes survival through enhancer looping at the BCL2A1 locus
J Dai, ED SoRelle, E Heckenberg, L Song, JM Cable… - Mbio, 2024 - Am Soc Microbiol
… + B cells complete the transformation into LCLs and express … an active CD40 receptor that
signals constitutively through … EBV infection of B cells phenocopies several important facets of …
signals constitutively through … EBV infection of B cells phenocopies several important facets of …
Epstein-Barr virus promotes survival through germinal center light zone chromatin architecture
… cells suggests that EBV phenocopies GC biology to enhance … in LCLs leads to constitutive
activation of extrinsic apoptosis … NFκB signaling in the form of CD40 ligation in uninfected B …
activation of extrinsic apoptosis … NFκB signaling in the form of CD40 ligation in uninfected B …
[HTML][HTML] Epstein-Barr virus perpetuates B cell germinal center dynamics and generation of autoimmune-associated phenotypes in vitro
… The ability of EBV infection to phenocopy elements of the GC reaction in the … CD40
signaling, and LMP2A, which downregulates MHC class II expression and mimics a constitutively …
signaling, and LMP2A, which downregulates MHC class II expression and mimics a constitutively …
Critical review of Epstein–Barr virus microRNAs relation with EBV‐associated gastric cancer
… for comprising NLRP3 inflammasome and converting pro-IL-… signaling pathways, including
mimics CD40 signaling and … -BART target mRNAs to phenocopy their antiapoptotic effect in …
mimics CD40 signaling and … -BART target mRNAs to phenocopy their antiapoptotic effect in …
[HTML][HTML] TRAF3 can interact with GMEB1 and modulate its anti-apoptotic function
G Kotsaris, D Kerselidou, D Koutsoubaris… - Journal of Biological …, 2020 - Springer
… inhibit the function of TRAF3 lead to constitutively active NF-… Yeast colonies co-transformed
with a plasmid expressing a … LMP1 is an oncoprotein expressed by the Epstein Barr virus (…
with a plasmid expressing a … LMP1 is an oncoprotein expressed by the Epstein Barr virus (…
The Call Is Coming from Inside the Cell: B Cell STAT3 Suppression of Interferon Signaling Aids in the Establishment of Latency of Murine Gammaherpesvirus 68
CH Hogan - 2023 - search.proquest.com
… the oncogenic gammaherpesviruses Epstein-Barr virus and … that mimics CD40 signaling
to constitutively activate NF-κB, … AD-HIES mice phenocopy patients living with AD-HIES, with …
to constitutively activate NF-κB, … AD-HIES mice phenocopy patients living with AD-HIES, with …
[PDF][PDF] Epstein-Barr virus evades restrictive host chromatin closure by subverting B cell activation and germinal center regulatory loci
… Successful infection substantially phenocopies activated, germinal … EBV transformation.Chromatin
closure in EBV-induced arrest was enriched at loci linked to B cell activation, signaling…
closure in EBV-induced arrest was enriched at loci linked to B cell activation, signaling…
[HTML][HTML] Genetically Engineered Mouse Models Support a Major Role of Immune Checkpoint-Dependent Immunosurveillance Escape in B-Cell Lymphomas
Q Lemasson, H Akil, J Feuillard… - Frontiers in …, 2021 - frontiersin.org
… models are globally useful for phenocopying human B-cell … the constitutively activated NF-κB
as it is in Epstein Barr Virus (… is due to specific B-cell expression of a chimeric LMP1/CD40 …
as it is in Epstein Barr Virus (… is due to specific B-cell expression of a chimeric LMP1/CD40 …
[HTML][HTML] Proliferative signals in chronic lymphocytic leukemia; what are we missing?
MV Haselager, AP Kater, E Eldering - Frontiers in oncology, 2020 - frontiersin.org
… of the Epstein-Barr viral Latent Membrane Protein 1, mimicking constitutively active CD40 …
modulate BCR responsiveness and thereby phenocopy the signaling dysfunction in CLL (71…
modulate BCR responsiveness and thereby phenocopy the signaling dysfunction in CLL (71…