From systemic inflammation to myocardial fibrosis: the heart failure with preserved ejection fraction paradigm revisited

WJ Paulus, MR Zile - Circulation research, 2021 - Am Heart Assoc
… This new evidence paves the road for future heart failure with … below the initial values after
imposition of the volume load. This … trend namely a lower hazard ratio for nonischemic heart

Heart failure with preserved ejection fraction: recent concepts in diagnosis, mechanisms and management

AB Gevaert, R Kataria, F Zannad, AJ Sauer, K Damman… - Heart, 2022 - heart.bmj.com
Recent developments in HFpEF management … In the TOPCAT-Americas trial, a post-hoc
analysis showed no sex differences in the primary composite outcome, but women had a greater …

Current prevalence, incidence, and outcomes of heart failure with preserved ejection fraction

DH Cho, BS Yoo - Heart Failure Clinics, 2021 - heartfailure.theclinics.com
… on the definition of HFpEF and current trends in prevalence, incidence, and outcomes. … and
biomarkers that reflect the mechanical stretch of the myocardium (BNP and NT-proBNP) were …

Heart failure with preserved ejection fraction: a review

MM Redfield, BA Borlaug - Jama, 2023 - jamanetwork.com
… Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction.  … This
review summarizes current evidence regarding the epidemiology, pathophysiology, clinical …

Temporal trends in the burden of heart failure

DZL Chan, AJ Kerr, RN Doughty - Internal Medicine Journal, 2021 - Wiley Online Library
… evaluate recent international trends in heart failure incidence, … preserved ejection fraction,
and a higher prevalence of non-… be due to improved survival following myocardial infarction, 8 …

Heart failure with preserved ejection fraction: JACC scientific statement

BA Borlaug, K Sharma, SJ Shah, JE Ho - Journal of the American College …, 2023 - Elsevier
… As we examine the global scope and secular trends of this disease… Recently developed
scoring systems (discussed later in this paper… Recent studies have demonstrated that myocardial

[HTML][HTML] Epidemiology and pathogenesis of heart failure with preserved ejection fraction

N Nair - Reviews in cardiovascular medicine, 2020 - imrpress.com
… Newer insights into myocardial remodeling have led to an interesting finding of abnormal …
In a recent study of temporal trends from 1990 to 2009 The temporal trends in heart failure

[HTML][HTML] Heart failure with preserved ejection fraction: the major unmet need in cardiology

CY Shim - Korean Circulation Journal, 2020 - synapse.koreamed.org
… Here, we review recent evidences and unsolved problems about … of HFpEF, there is a trend
to classify several key phenotypes … Moreover, since the supine position increases myocardial

Pathophysiology of heart failure with preserved ejection fraction

JC Youn, Y Ahn, HO Jung - Heart Failure Clinics, 2021 - heartfailure.theclinics.com
… unmet clinical needs in the current cardiovascular medicine. … , multiorgan disease, increased
myocardial tissue stiffness is … cardiomyocyte passive stiffness and myocardial fibrosis. …

Heart failure with preserved ejection fraction: insights into diagnosis and pathophysiology

SF Nagueh - Cardiovascular Research, 2021 - academic.oup.com
… Molecular imaging techniques were utilized in post-myocardial infarction setting to detect
new collagen deposition using RGD (arginine, glycine, aspartate) labelled with technetium-99m…