Phase 2 study of pembrolizumab for measurable residual disease in adults with acute lymphoblastic leukemia

RD Cassaday, KLA Garcia, JR Fromm… - Blood …, 2020 - ashpublications.org
… These data can be compared with ongoing anti-PD-1 combination … inevitably heralds frank
hematologic relapse without additional … Clinical significance of minimal residual disease …

Treatment-free remission in patients with chronic myeloid leukaemia

DM Ross, TP Hughes - Nature reviews Clinical oncology, 2020 - nature.com
… might be loss of cytogenetic or haematological remission, as has … , an ongoing low risk of
molecular relapse exists 56 — the … in which loss of undetectable minimal residual disease is the …

Clinical values of gene alterations as marker of minimal residual disease in non-M3 acute myeloid leukemia

T Yu, J Chi, L Wang - Hematology, 2021 - Taylor & Francis
… presence of residual LSCs following remission increases the … clone with EVI1 upregulation
is persistent in BM follow-up [… different molecular characteristic of AML, but every molecular

[HTML][HTML] The importance of minimal residual disease for detection of late relapse in Bprecursor acute lymphoblastic leukemia

M Virijevic, N Kraguljac-Kurtovic, N Pantic… - Hippokratia, 2022 - ncbi.nlm.nih.gov
… A 30-year-old woman was admitted to the hematology clinic … We continued to monitor
MRD with MFC. The MRD levels in … In summary, considering the late molecular relapse in our …

[HTML][HTML] A multicenter total therapy strategy for de novo adult Philadelphia chromosome positive acute lymphoblastic leukemia patients: final results of the GIMEMA …

S Chiaretti, M Ansuinelli, A Vitale, L Elia… - …, 2021 - ncbi.nlm.nih.gov
… CMR continued dasatinib until progression or minimal residual … a hematologic relapse,
one experienced a molecularremissions and long-term survival can be achieved with a …

Using measurable residual disease to optimize management of AML, ALL, and chronic myeloid leukemia

SE Dekker, D Rea, JM Cayuela, I Arnhardt… - American Society of …, 2023 - ascopubs.org
… discuss ongoingcomplete hematologic response, residual leukemic cells can be evaluated
by reliable techniques in routine practice including conventional cytogenetics and molecular

Defining the undetectable: the current landscape of minimal residual disease assessment in multiple myeloma and goals for future clarity

BT Diamond, E Rustad, K Maclachlan, K Thoren, C Ho… - Blood reviews, 2021 - Elsevier
… For as long as hematologists and oncologists have been utilizing … Molecular MRD testing
has since evolved to employ highly … There are ongoing efforts in collaboration with regulatory …

Significance of minimal residual disease in pediatric mixed phenotype acute leukemia: a multicenter cohort study

MJ Oberley, SS Raikar, GB Wertheim, J Malvar… - Leukemia, 2020 - nature.com
… In the meantime, to ensure continued support, we are … Cytogenetic abnormalities were not
associated with positive EOI … a MRD-negative complete remission. Analysis of clinical features …

[PDF][PDF] Minimal Residual Disease Assessment and Genetic Alterations in Childhood Acute Lymphoblastic Leukemia.

EH Aktekin, I Kozanoglu, FI Sahin, A Erbay… - … Journal of Hematology & …, 2023 - uhod.org
… count on day 8, remission evaluation of bone marrow on … , and continuous measurements
as mean, minimum-maximum, … MRD analysis and cytogenetic and molecular profiling of the …

Early peripheral blast cell clearance predicts minimal residual disease status and refines disease prognosis in acute myeloid leukemia

F Mannelli, G Gianfaldoni, S Bencini… - … of Hematology, 2020 - Wiley Online Library
… -based threshold that defines complete remission (CR). The … cytogenetics, histopathology,
and molecular genetics, and … the Kruskal-Wallis test for continuous variables, and Pearson's chi…