The importance of breast adipose tissue in breast cancer

C Kothari, C Diorio, F Durocher - International journal of molecular …, 2020 - mdpi.com
… cells of the breast including adipose tissue. In this review, we will discuss the importance
of the breast adipose tissue ”organ” in breast development through puberty, pregnancy and …

Diabetes mellitus and its metabolic complications: the role of adipose tissues

L Dilworth, A Facey, F Omoruyi - International journal of molecular …, 2021 - mdpi.com
… This review will highlight the role of adipose tissue in the pathogenesis of diabetes and
the … Among the pro-inflammatory cytokines, tumor necrosis factor-alpha is one of the most …

Cancer-associated adipocytes: emerging supporters in breast cancer

C Zhao, M Wu, N Zeng, M Xiong, W Hu, W Lv… - … & Clinical Cancer …, 2020 - Springer
… Adipocytes and breast cancer Adipose tissue plays an important physiological role as a …
It has aroused great interest in understanding the development and renewal of adipose tissue

The role of adipose tissue senescence in obesity-and ageing-related metabolic disorders

Z Liu, KKL Wu, X Jiang, A Xu, KKY Cheng - Clinical science, 2020 - portlandpress.com
development and progression of cancer, mainly, by induction of cell cycle arrest, although
it has been shown to induce tumor … of senescent cells in metabolic tissues (including liver, …

Adipose tissue aging: mechanisms and therapeutic implications

MY Ou, H Zhang, PC Tan, SB Zhou, QF Li - Cell death & disease, 2022 - nature.com
… Together, we suggest that adipose tissue plays a key role in the aging process and … develop
hypertension [126]. Obesity-induced adipose tissue inflammation may be a driver of cancer

Adipose tissue fibrosis in obesity: etiology and challenges

G Marcelin, EL Gautier, K Clément - Annual review of physiology, 2022 - annualreviews.org
adipose tissue (WAT) is a complex tissue with major regulatory functions. In addition to playing
a well-known role … , mirroring the cancer therapy using antiangiogenic agent to limit tumor

Cellular heterogeneity in adipose tissues

S Corvera - Annual review of physiology, 2021 - annualreviews.org
… constituting mouse and human adipose tissues. In addition to … together orchestrate adipose
tissue development and functions. … into adipose tissues and their role in metabolic disease. …

Adipose-tissue plasticity in health and disease

A Sakers, MK De Siqueira, P Seale, CJ Villanueva - Cell, 2022 - cell.com
… , we now appreciate that adipose tissue regulates many aspects of … A crucial property of
adipose tissue is its high degree of … the risk of developing numerous cancers and predisposes to …

[HTML][HTML] Adipose tissue: physiology to metabolic dysfunction

AJ Richard, U White, CM Elks, JM Stephens - Endotext [Internet], 2020 - ncbi.nlm.nih.gov
adipose tissue is expanding. Just in the past decade, substantial advances have led to new
insights into the contributions of adipose tissue … leptin plays a role in breast cancer (111). As …

The role of lipids in cancer progression and metastasis

M Martin-Perez, U Urdiroz-Urricelqui, C Bigas… - Cell metabolism, 2022 - cell.com
… high fat intake in Western diets. Thus, metabolic interventions aiming to reduce lipid availability
to cancer … therapeutic opportunities to prevent cancer progression and treat metastasis. …