… homologue, Spt5 13 is ubiquitously bound to elongating pol II and … facilitates termination
by slowing pol II down and turning it into a “sitting duck” through dephosphorylation of Spt5…

… ) promotes Pol II slowing which is caused by dephosphorylation of SPT5 by PNUTS/PP1 …
uncommon in cells and might conflict with RNA quality control. This is suggested by findings …

… implicated in Spt5-CTR dephosphorylation and Pol II deceleration … that PP1 promotes Pol II
slowing and termination through Spt5 … controls transcription exit through PP1-dependent Spt5 …

… Here, we demonstrate that the RNA polymerase II (RNAPII) C-… WDR82 also promotes
RNAPII-CTD dephosphorylation and … by proteasome inhibition in control cells but less so in PNUTS…

… premature termination at promoters ( … stability to facilitate release of RNA Pol II from
promoter-proximal regions … To test whether SPT5 depletion affects the phosphorylation status of …

… mediated de-phosphorylation of both Pol II and Spt5 regulates the … Additionally, we
show that Pol II is a direct substrate for PNUTS-PP1-… Pol II speed is reduced by the PP1-mediated …

… release is facilitated by the PTEFb phosphorylation of the RNA Pol II elongation factor, Spt5.
… Alternatively, the active removal of RNA Pol II by premature termination could contribute to …

… In yeast, PP1 dephosphorylation of both Pol II CTD and Spt5 is … PP1-1 facilitates Pol II-CTD
dephosphorylation PP1-… a conserved PNUTSPP1 controlled mechanism of Pol II termination …

… The RNA polymerase II (RNAPII) transcription cycle is … stages of initiation, elongation,
termination, and recycling of … that RPB1 linker phosphorylation promotes SPT6 recruitment …

… The transcription cycle of RNA polymerase II (RNAPII) is … , ensuring fine control of elongation
and termination. Much is still … of indicated RNAPII and SPT5 phosphorylation marks along …