[HTML][HTML] Natural Products for Acetaminophen-Induced Acute Liver Injury: A Review

X Li, R Lao, J Lei, Y Chen, Q Zhou, T Wang, Y Tong - Molecules, 2023 - mdpi.com
hepatotoxicity of APAP and explore potential treatment strategies using a mouse model of
APAP-induced liver injuryalleviating liver damage and improving liver function through various …

Corilagin alleviates intestinal ischemia/reperfusion injury by relieving oxidative stress and apoptosis via AMPK/Sirt1-autophagy pathway

B Li, W Li, M Zheng, Y Wang, Y Diao… - Experimental …, 2023 - journals.sagepub.com
… and restore autophagic flux to alleviate nonalcoholic fatty liver disease … alleviate
acetaminophen-induced liver injury, suggesting the possibility of CA regulating autophagy by …

Cynarin alleviates acetaminophen-induced acute liver injury through the activation of Keap1/Nrf2-mediated lipid peroxidation defense via the AMPK/SIRT3 signaling …

L Zhao, X Zhang, Z Chen, Y Lai, J Xu, R Zhou, P Ma… - Food & Function, 2024 - pubs.rsc.org
… Additionally, Cyn promoted the dissociation of Nrf2 from Keap1, enhancing the … alleviates
APAP-induced ALI by enhancing the Keap1/Nrf2-mediated lipid peroxidation defense via

Guavinoside B from Psidium guajava alleviates acetaminophen-induced liver injury via regulating the Nrf2 and JNK signaling pathways

Y Li, J Xu, D Li, H Ma, Y Mu, X Huang, L Li - Food & function, 2020 - pubs.rsc.org
… of JNK into mitochondria, thereby further increasing mitochondrial oxidative stress and causing
the … Our result was consistent with the previous report of corilagin, which was classified as …

[HTML][HTML] Corilagin decreases insulin resistance in polycystic ovary syndrome rat model through regulating AMPK/GSK3β pathway

B Lv, X Li, H Wang - Translational Cancer Research, 2020 - ncbi.nlm.nih.gov
Corilagin reduced DHEA-induced increase of serum glucose … , Corilagin efficiently decreased
acetaminophen-induced … cells via the up-regulation of the AMPK/GSK3β-Nrf2 signaling …

Current etiological comprehension and therapeutic targets of acetaminophen-induced hepatotoxicity

A Chowdhury, J Nabila, IA Temitope, S Wang - Pharmacological research, 2020 - Elsevier
… also improve mitochondrial energy metabolism through ATP maintenance [19]. Currently, NAC
is administered as the treatment for APAP-induced liver toxicity (… ) reduces survivability but …

[HTML][HTML] Ethanol Extract of Rosa rugosa Ameliorates Acetaminophen-Induced Liver Injury via Upregulating Sirt1 and Subsequent Potentiation of LKB1/AMPK/Nrf2 …

Y Lei, X Lei, A Zhu, S Xie, T Zhang, C Wang, A Song… - Molecules, 2023 - mdpi.com
… has the potential to alleviate APAP liver injury and support the … improve APAP-provoked
liver injury via activating Nrf2 [22,56]. It has been unveiled previously that rose flowers enhance

Total flavonoids of Broussonetia papyrifera alleviate non-alcohol fatty liver disease via regulating Nrf2/AMPK/mTOR signaling pathways

Q Wang, Y Wei, Y Wang, Z Yu, H Qin, L Zhao… - … et Biophysica Acta (BBA …, 2024 - Elsevier
… The AMPK/GSK3β/Nrf2 … in improving lung injury [44] and liver injury [45] in the study by
Authors (2019). Similarly, TFBP in our study activated AMPK/GSK3β/Nrf2 thereby improving

Theaflavine inhibits hepatic stellate cell activation by modulating the PKA/LKB1/AMPK/GSK3β cascade and subsequently enhancing Nrf2 signaling

G Shu, H Sun, T Zhang, A Zhu, X Lei, C Wang… - European Journal of …, 2023 - Elsevier
… of PKA and LKB1 and alleviates liver injury caused by oxidative … TF-mediated regulation of
the AMPK/GSK3β/Nrf2 cascade, we … Moreover, the natural polyphenol corilagin triggers LKB1 …

Corilagin attenuates morphine-induced BV2 microglial activation and inflammation via regulating TLR2-mediated endoplasmic reticulum stress

S Guan, F Miao, D Wang, J Hu… - The Journal of …, 2023 - jstage.jst.go.jp
… effectively alleviated morphine-induced neuroinflammation and microglia activation through
… 1A, BV-2 cells were treated with increasing concentrations of Cori (0.1, 1 and 10 μM) for 24 …