From gene identifications to therapeutic targets for asthma: Focus on great potentials of TSLP, ORMDL3, and GSDMB

Y Zhang - Chinese Medical Journal Pulmonary and Critical Care …, 2023 - mednexus.org
… In China, the overall prevalence of asthma was 4.2%, … After discovery of the association
between the polymorphisms of … other relevant cytokines expressed in the airway epithelium to …

[HTML][HTML] Relationship between common interleukin 1-beta gene polymorphisms and the risk of gestational disorders: An updated meta-analysis

M Harati-Sadegh, S Sargazi, H Taheri… - Medical Journal of the …, 2021 - ncbi.nlm.nih.gov
… that polymorphisms could alter cytokine production levels and the strength of … this cytokine
in pregnancy (45). A wealth of studies have reported the increased level of IL-1β in plasma of …

[HTML][HTML] The Interleukin-1 (IL-1) superfamily cytokines and their single nucleotide polymorphisms (SNPs)

P Behzadi, AS Sameer, S Nissar, MZ Banday… - Journal of immunology …, 2022 - hindawi.com
… divergence among cytokine genes (such as IL genes), some … (rs1143634) gene polymorphism
was found between SLE … till date, and all have been implicated in asthma susceptibility (…

Coronavirus: pure infectious disease or genetic predisposition

F Darbeheshti, H Abolhassani, M Bashashati… - … Disease-COVID-19, 2021 - Springer
… in December 2019 in Wuhan, China. To date, our knowledge about its … IL-6 gene
polymorphisms are other potential factors … the risk of asthma through autophagy genes could …

[HTML][HTML] Research progress of immune balance and genetic polymorphism in unexplained recurrent abortion

Y Kang, Q Xie, S Chen, Q Li, X Dong… - Exploration of …, 2023 - explorationpub.com
Among all these related genes, the IL-6 gene is the most … -inflammatory gene polymorphism
in URSA patients, and IL-6-… prove the association between this specific polymorphism and …

[HTML][HTML] The Role of Interleukin 6 in Periodontitis and Its Complications

M Mazurek-Mochol, T Bonsmann, M Mochol… - International Journal of …, 2024 - mdpi.com
… [80], in close agreement with results in a Northwestern Chinese Han population [79]. The …
a statistically significant association between the IL-6-597 gene polymorphism and a chronic …

Investigation of the linkage between TNF-alfa rs1800629 polymorphism and preeclampsia risk: A meta-analysis

MS Hossen, MA Aziz, MA Barek, MS Islam - Cytokine, 2024 - Elsevier
link of the TNF-alfa polymorphism to the preeclampsia risk among the Black population, no
… yet known which genes are involved or how particular genetic variants affect preeclampsia. …

Association of IL-16 rs11556218 T/G polymorphism with the risk of developing type 2 diabetes mellitus

DG Mohammad, H Omar, TB El-Abaseri… - Journal of Diabetes & …, 2021 - Springer
… to many inflammatory diseases such as asthma or Crohn’s … of different cytokines [4]. In
this study, we are studying the … A study on a Chinese Han population showed similar results …

[HTML][HTML] COVID-19 and individual genetic susceptibility/receptivity: role of ACE1/ACE2 genes, immunity, inflammation and coagulation. Might the double X …

D Gemmati, B Bramanti, ML Serino… - International journal of …, 2020 - mdpi.com
… Rapidly, it became an epidemic in China and has now … Several gene polymorphisms
have been listed among thosecytokines, confirm an inverse correlation between ACE2 …

[HTML][HTML] The association between the rs4987105 of 5-lipoxygenase (ALOX5) gene and gestational glucose metabolism in Chinese population

X Li, J Su, S Chen, S Lin, X Zheng, B Wang, K Yao… - BMC Research …, 2020 - Springer
… balance between pro- and anti-inflammatory cytokines is … including metabolic disorders,
asthma,cardiovascular diseases, … close to the MAF in Southern Han Chinese (23%) and the …