[HTML][HTML] Connectivity of the corticostriatal and thalamostriatal systems in normal and parkinsonian states: an update
AC Martel, A Galvan - Neurobiology of disease, 2022 - Elsevier
… of diverse cortical inputs onto the striatal interneurons and SPNs… IT and PT cortical neurons
project to both projection neurons … by side glutamatergic inputs to GABAergic interneurons. In …
project to both projection neurons … by side glutamatergic inputs to GABAergic interneurons. In …
What Is the Role of the Intralaminar Thalamic Input to the Striatum and Its Potential Implications in Parkinson Disease?
E Benarroch - Neurology, 2023 - AAN Enterprises
… presynaptic suppression of cortical input to both direct and … but ultimately contributes to the
imbalance between the indirect (… contribute to movement initiation and rescued parkinsonian …
imbalance between the indirect (… contribute to movement initiation and rescued parkinsonian …
What's wrong with the striatal cholinergic interneurons in Parkinson's disease? Focus on intrinsic excitability
C Tubert, MG Murer - European Journal of Neuroscience, 2021 - Wiley Online Library
… ChIs activity ameliorates parkinsonian symptoms and modifies L-… that thalamic input is
stronger than cortical input in ChIs and … nicotinic receptors in GABAergic interneurons (Figure 2c). …
stronger than cortical input in ChIs and … nicotinic receptors in GABAergic interneurons (Figure 2c). …
[HTML][HTML] Striatal synaptic adaptations in Parkinson's disease
… from an imbalance in the excitability of striatal efferent projection … input to the striatum comes
from the cerebral cortex, the … in restoring running in mice that were parkinsonian. Thus, while …
from the cerebral cortex, the … in restoring running in mice that were parkinsonian. Thus, while …
Synaptic determinants of cholinergic interneurons hyperactivity during parkinsonism
M Padilla-Orozco, M Duhne… - Frontiers in Synaptic …, 2022 - frontiersin.org
… , not expressed in striatal projection neurons. Therefore, … inhibitory synaptic inputs onto CINs
during the Parkinsonian state … that excitatory glutamatergic inputs from cortex and thalamus …
during the Parkinsonian state … that excitatory glutamatergic inputs from cortex and thalamus …
[HTML][HTML] Loss of nigral excitation of cholinergic interneurons contributes to parkinsonian motor impairments
… dopamine inputs in Parkinson’s disease leads to imbalances … in the striatum, which is
thought to contribute to parkinsonian … inputs and cholinergic interneurons (ChIs) control striatal …
thought to contribute to parkinsonian … inputs and cholinergic interneurons (ChIs) control striatal …
[HTML][HTML] Cholinergic interneuron inhibition potentiates corticostriatal transmission in direct medium spiny neurons and rescues motor learning in parkinsonism
G Laverne, J Pesce, A Reynders, E Combrisson… - Cell Reports, 2022 - cell.com
… of GABAergic projection neurons in the striatum called … All parkinsonian mice used in this
study had DA depletion ≥70… of the striatum receiving direct inputs from the sensorimotor cortex. …
study had DA depletion ≥70… of the striatum receiving direct inputs from the sensorimotor cortex. …
Neuropathology of the basal ganglia in SNCA transgenic rat model of Parkinson's disease: Involvement of parvalbuminergic interneurons and glial-derived …
E Paldino, V D'angelo, M Massaro Cenere… - International Journal of …, 2022 - mdpi.com
… synapses from thalamus and cortex. Their axons generate … studied striatum morphology and
the specific subsets of neurons … An imbalance in the activity of cerebellar pathways has been …
the specific subsets of neurons … An imbalance in the activity of cerebellar pathways has been …
[HTML][HTML] Striatal glutamatergic hyperactivity in Parkinson's disease
F Campanelli, G Natale, G Marino, V Ghiglieri… - Neurobiology of …, 2022 - Elsevier
… Here we focus on the parkinsonian state, in which this striatal … changes in the striatum concurs
to the unbalance between direct … by excitatory input from cortical neurons during plateau …
to the unbalance between direct … by excitatory input from cortical neurons during plateau …
The impact of Parkinson's disease on striatal network connectivity and cortico-striatal drive: an in-silico study
… % of the neurons and the remaining 5% 15 are GABAergic and … transfer 91 of cortical inputs
to the striatum we activated dSPN … (and thalamus), we simulated a set of Parkinsonian dSPN …
to the striatum we activated dSPN … (and thalamus), we simulated a set of Parkinsonian dSPN …