[HTML][HTML] Connectivity of the corticostriatal and thalamostriatal systems in normal and parkinsonian states: an update

AC Martel, A Galvan - Neurobiology of disease, 2022 - Elsevier
… of diverse cortical inputs onto the striatal interneurons and SPNs… IT and PT cortical neurons
project to both projection neurons … by side glutamatergic inputs to GABAergic interneurons. In …

What Is the Role of the Intralaminar Thalamic Input to the Striatum and Its Potential Implications in Parkinson Disease?

E Benarroch - Neurology, 2023 - AAN Enterprises
… presynaptic suppression of cortical input to both direct and … but ultimately contributes to the
imbalance between the indirect (… contribute to movement initiation and rescued parkinsonian

What's wrong with the striatal cholinergic interneurons in Parkinson's disease? Focus on intrinsic excitability

C Tubert, MG Murer - European Journal of Neuroscience, 2021 - Wiley Online Library
… ChIs activity ameliorates parkinsonian symptoms and modifies L-… that thalamic input is
stronger than cortical input in ChIs and … nicotinic receptors in GABAergic interneurons (Figure 2c). …

[HTML][HTML] Striatal synaptic adaptations in Parkinson's disease

W Shen, S Zhai, DJ Surmeier - Neurobiology of disease, 2022 - Elsevier
… from an imbalance in the excitability of striatal efferent projectioninput to the striatum comes
from the cerebral cortex, the … in restoring running in mice that were parkinsonian. Thus, while …

Synaptic determinants of cholinergic interneurons hyperactivity during parkinsonism

M Padilla-Orozco, M Duhne… - Frontiers in Synaptic …, 2022 - frontiersin.org
… , not expressed in striatal projection neurons. Therefore, … inhibitory synaptic inputs onto CINs
during the Parkinsonian state … that excitatory glutamatergic inputs from cortex and thalamus …

[HTML][HTML] Loss of nigral excitation of cholinergic interneurons contributes to parkinsonian motor impairments

Y Cai, BE Nielsen, EE Boxer, J Aoto, CP Ford - Neuron, 2021 - cell.com
… dopamine inputs in Parkinson’s disease leads to imbalances … in the striatum, which is
thought to contribute to parkinsonianinputs and cholinergic interneurons (ChIs) control striatal

[HTML][HTML] Cholinergic interneuron inhibition potentiates corticostriatal transmission in direct medium spiny neurons and rescues motor learning in parkinsonism

G Laverne, J Pesce, A Reynders, E Combrisson… - Cell Reports, 2022 - cell.com
… of GABAergic projection neurons in the striatum called … All parkinsonian mice used in this
study had DA depletion ≥70… of the striatum receiving direct inputs from the sensorimotor cortex. …

Neuropathology of the basal ganglia in SNCA transgenic rat model of Parkinson's disease: Involvement of parvalbuminergic interneurons and glial-derived …

E Paldino, V D'angelo, M Massaro Cenere… - International Journal of …, 2022 - mdpi.com
… synapses from thalamus and cortex. Their axons generate … studied striatum morphology and
the specific subsets of neurons … An imbalance in the activity of cerebellar pathways has been …

[HTML][HTML] Striatal glutamatergic hyperactivity in Parkinson's disease

F Campanelli, G Natale, G Marino, V Ghiglieri… - Neurobiology of …, 2022 - Elsevier
… Here we focus on the parkinsonian state, in which this striatal … changes in the striatum concurs
to the unbalance between direct … by excitatory input from cortical neurons during plateau …

The impact of Parkinson's disease on striatal network connectivity and cortico-striatal drive: an in-silico study

I Carannante, M Scolamiero, JJJ Hjorth… - Network …, 2024 - direct.mit.edu
… % of the neurons and the remaining 5% 15 are GABAergic and … transfer 91 of cortical inputs
to the striatum we activated dSPN … (and thalamus), we simulated a set of Parkinsonian dSPN …