… of cigarette smoking exposure ovalbumin-induced asthma is alleviated by CpG oligodeoxynucleotides via affecting dendritic cell-mediated Th17 polarization

H Li, Y Lin, Q Ye, X Yang, X Zou, H Yang… - International …, 2020 - Elsevier
… of CpG oligodeoxynucleotides (CpG-ODNs) to inhibit airway … We found that combination of
CS and OVA could induce … , while reduced amounts of Th1-cytokine (IFN-γ) were detected in …

CpG Oligodeoxynucleotides Attenuate OVA-Induced Allergic Airway Inflammation via Suppressing JNK-Mediated Endoplasmic Reticulum Stress

HY Zhang, QM Xie, CC Zhao, JF Sha… - Journal of Asthma …, 2021 - Taylor & Francis
… Citation8 Synthetic CpG-oligodeoxynucleotide (CpG-ODN), … cells, dendritic cells and other
types of cells, it induces Th1 response, and secretion of IFN-γ and IL-12 which potently inhibit

CpG adjuvant in allergen-specific immunotherapy: finding the sweet spot for the induction of immune tolerance

G Montamat, C Leonard, A Poli, L Klimek… - Frontiers in …, 2021 - frontiersin.org
Th1 response can inhibit Th2 and allergy responses through … 3) prevented cockroach-induced
allergic asthma in a mouse … CpG-ODN has been shown to induce an immutable IFN-γ-…

Toll-like receptor agonists as adjuvants for allergen immunotherapy

ME Kirtland, DC Tsitoura, SR Durham… - Frontiers in …, 2020 - frontiersin.org
… molecular, cellular, and humoral mechanisms that inhibit the … sensitisation in a cockroach
induced-allergic asthma model, … of CpG ODN were mediated through IL-12 promoted IFN-γ

[PDF][PDF] Relationship between toll-like receptor 7 and indoleamine 2, 3-dioxygenase in mice with asthma and the effect of interferon-γ on asthma

W Li, C Lu, Q Feng, Y Zhang - INTERNATIONAL JOURNAL OF …, 2020 - e-century.us
… model of house dust mite asthma was established and treated with IFN-γ at 100 U/mL, …
CpG Oligodeoxynucleotide inhibits Cockroach-Induced asthma via induction of IFN-γ+ Th1 Cells

[HTML][HTML] The Use of Chitosan Nanoparticles for Delivery of CpG ODN in Treatment of Allergic Balb/C Mice

FC Iswanti, QH Putri, AR Prijanti, S Djauzi… - … of Biochemistry & …, 2023 - ncbi.nlm.nih.gov
… of naïve T cells to Th2 type cells, inhibiting Th1 activation. In a study … , the group treated with
CpG ODN showed higher IFN-γ levels in the … CpG ODN will induce the secretion of IL-12 and …

TLR9–IL-2 axis exacerbates allergic asthma by preventing IL-17A hyperproduction

Y Murakami, T Ishii, H Nunokawa, K Kurata, T Narita… - Scientific Reports, 2020 - nature.com
… IL-12, which is the main cytokine that induces Th1 cellcells, which secrete a high level
of IFN-γ, may produce IFN-γinhibited the Il12b mRNA expression caused by CpG-ODN

Interplay of IL-33 and IL-35 Modulates Th2/Th17 Responses in Cigarette Smoke Exposure HDM-Induced Asthma

J Liu, B Su, P Tao, X Yang, L Zheng, Y Lin, X Zou… - Inflammation, 2024 - Springer
… -ODNs can inhibit disease progression, we followed the protocol … and IFN-γ levels were
reduced in the HDM/CSE group … or induction of IL-35 can collaborate with DCs to inhibit the …

Flagellin conjugated Per a 10 and its T cell peptides attenuate airway inflammation and restore cellular function

R Mishra, S Sharma, N Arora - Immunologic Research, 2024 - Springer
… -13 and Th1 cytokine d IFN-γ, e IL-10 and f TGF-β using ELISA… cell peptides in the
cockroach-induced allergic mice model. … ) and blocking IgG2a antibodies with IgE inhibition [26]. …

Decoding the role of DNA methylation in allergic diseases: from pathogenesis to therapy

R Han, D Zhu, J Sha, B Zhao, P Jin, C Meng - Cell & Bioscience, 2024 - Springer
… Additionally, rhinovirus infections are known to induce … of the IFN-γ promoter in patients
with allergic asthma. … , potentially related to the inhibition of the JNK signaling pathway, as …