… (BMP15) are oocyte-secreted members of the transforming growth factor-β (TGF-β) superfamily
( … Cumulin, an oocyte-secreted heterodimer of the transforming growth factor-β family, is a …

… The focus of this review is on the transforming growth factor-β (TGFB) superfamily and
interferon-τ (IFNT). These have been the subject of previous reviews (Knight and Glister 2003, …

Oocyte in vitro maturation can be improved by mimicking the intra-follicular environment.
Oocyte, cumulus cells, granulosa cells, and circulating factors act as meiotic regulators in …

… To determine the role of oocyte-secreted factors (OSFs) such as growth differentiation
factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) in IGF2 production by hGCs. …

… as oocyte secreted factors (OSF) that belong to the transforming growth factor-β (TGF-β)
family, growth … could prevail as heterodimers (GDF-9/BMP-15), later known as cumulin, which …

… The transforming growth factor-β (… cumulin, GDF9 and BMP15; which indicated that cumulin
contains two unique type I receptor binding epitopes, one on either side of its heterodimeric …

… , proteins derived from transforming growth factor-β (TGFβ) … can form a stable heterodimer
complex (named cumulin). … GDF9 and BMP15, as oocyte-secreted paracrine factors, control …

… In the current study, to be sure of treatment with cumulin per se, we prevented 103 heterodimer
… This study provides a detailed exploration of the mechanisms by which oocyte-secreted …

… growth factor (EGF)-related peptides such as amphiregulin (AREG) and/or epiregulin (EREG),
effect of TGF-β family members including growth … -MAS), the growth factor midkine (MDK), …

… Oocytes secrete members of the transforming growth factor-… exclude the effects of the
oocyte-secreted factors. This enabled … Although it is not certain whether they formed cumulin …