Application of mesenchymal stem cells in inflammatory and fibrotic diseases

JS Ryu, EJ Jeong, JY Kim, SJ Park, WS Ju… - International journal of …, 2020 - mdpi.com
… array of inflammatory and autoimmune disorders, such as graft-versus-host disease (GVHD), …
Moreover, MSCs derived from ongoing sick donors are unable to suppress disease upon …

[HTML][HTML] Mesenchymal stem cell therapy: hope for patients with systemic lupus erythematosus

A Li, F Guo, Q Pan, S Chen, J Chen, H Liu… - Frontiers in …, 2021 - frontiersin.org
… with autoimmune diseases, such as SLE (11). Therefore, autologous hematopoietic stem
cell (… Recent studies have revealed that the innate immune response plays a vital role in SLE …

Therapeutic applications of mesenchymal stem cells:: a comprehensive review

P Samadi, S Saki, H Manoochehri… - … Stem Cell Research …, 2021 - ingentaconnect.com
… , along with their differentiation characteristics, has established MSCs as a suitable candidate
for immunotherapy applications in the treatment of illnesses such as autoimmune diseases

Effects of mesenchymal stromal cells on regulatory T cells: Current understanding and clinical relevance

N Negi, MD Griffin - Stem Cells, 2020 - academic.oup.com
… immunological diseases. In this review, we critically assess recent translational research
related … base to be further exploited for the treatment of autoimmune disorders and transplants. …

Mesenchymal stem/stromal cells for rheumatoid arthritis treatment: an update on clinical applications

M Lopez-Santalla, R Fernandez-Perez, MI Garin - Cells, 2020 - mdpi.com
… attractive new approach to address unresolved treatment issuestherapy was conducted in
2010 by the Stem Cell Research … In this study, 10 patients with different autoimmune diseases

… stem cell transplantation and cellular therapies for autoimmune diseases: overview and future considerations from the Autoimmune Diseases Working Party (ADWP) …

T Alexander, R Greco - Bone marrow transplantation, 2022 - nature.com
cellular therapies, exploiting mesenchymal stem cells, regulatory T cells and potentially CAR-T
cell therapies, … Overall, we discuss past and current indications, efficacy, associated risks …

The immunomodulatory effects of mesenchymal stromal cell‐based therapy in human and animal models of systemic lupus erythematosus

F Radmanesh, M Mahmoudi, E Yazdanpanah… - IUBMB …, 2020 - Wiley Online Library
autoimmune diseases, in particular SLE. This report aims to review the beneficial and
therapeutic … Contrary to these reports, the ongoing tissue inflammation and organ damage in …

Stem cell therapies for autoimmune hepatitis

A Lotfy, A Elgamal, A Burdzinska, AA Swelum… - Stem Cell Research & …, 2021 - Springer
… effects in autoimmune diseases such as multiple sclerosis. … Mesenchymal stem cells (MSCs)
therapy possess numerous … The current review aimed to summarize studies focused on …

Mesenchymal stromal cell based therapies for the treatment of immune disorders: recent milestones and future challenges

A Gonzalez-Pujana, M Igartua… - Expert opinion on …, 2020 - Taylor & Francis
… treatment of autoimmune diseases such as MS, systemic lupus erythematosus or amyotrophic
lateral sclerosis [Citation26]. MS is a T-cell mediated autoimmune disorder characterized …

Mesenchymal stem cells: Biological characteristics and application in disease therapy

S Lou, Y Duan, H Nie, X Cui, J Du, Y Yao - Biochimie, 2021 - Elsevier
Mesenchymal stem cells (MSCs) are a type of adult stem cell … , in the present work, we first
discussed the application of … preclinical studies of MSC treatment in autoimmune diseases, …