Intranasal administration of small extracellular vesicles derived from mesenchymal stem cells ameliorated the experimental autoimmune encephalomyelitis

A Fathollahi, SM Hashemi, MHM Hoseini… - International …, 2021 - Elsevier
current study was to evaluate the effect of intranasal administration of mesenchymal stem cells
(… EAE model is a prototypic T cell-mediated model of autoimmune diseases. Therefore, we …

Therapeutic potential of mesenchymal stromal stem cells in rheumatoid arthritis: a systematic review of in vivo studies

A Karamini, A Bakopoulou, D Andreadis… - Stem cell reviews and …, 2020 - Springer
… A recent review highlights a trend for the investigation of tissue … Mesenchymal stem cell
transplantation (MSCT) enhances the clinical characteristics of various autoimmune diseases, …

Immunomodulatory mechanisms of mesenchymal stem cells and their potential clinical applications

Y Huang, Q Wu, PKH Tam - International Journal of Molecular Sciences, 2022 - mdpi.com
… strategy to treat immune disorders, including autoimmune diseases and incurable inflammatory
diseases. Here we review the recent exploration of immunomodulatory mechanisms of …

[HTML][HTML] A narrative review of research advances in mesenchymal stem cell therapy for asthma

X Yu, L Yu, B Guo, R Chen, C Qiu - Annals of translational …, 2020 - ncbi.nlm.nih.gov
… -versus-host disease, inflammatory diseases, as well as neurological, bone and cartilage,
cardiovascular, and autoimmune diseases and so on (10). During recent years, there have …

Mesenchymal stem cell-based therapy for retinal degenerative diseases: experimental models and clinical trials

V Holan, K Palacka, B Hermankova - Cells, 2021 - mdpi.com
… [41] and suppressed the incidence and severity of autoimmune diseases [42,43]. These …
In our recent study we have observed that NaIO 3 increases the expression of genes for …

Mesenchymal stromal cells for systemic sclerosis treatment

D Farge, S Loisel, P Lansiaux, K Tarte - Autoimmunity Reviews, 2021 - Elsevier
… Systemic sclerosis (SSc) is a rare chronic autoimmune disease with a … as disease-modifying
therapies in SSc. In this context, stem cell therapies are emerging as a new therapeutic

[HTML][HTML] The immunomodulatory effects of mesenchymal stem cells on regulatory B cells

J Liu, Q Liu, X Chen - Frontiers in Immunology, 2020 - frontiersin.org
… the current findings … studies, the roles of MSCs in regenerative medicine have attracted
widespread attention, especially their immunomodulatory effects on autoimmune diseases and …

Potential methods for improving the efficacy of mesenchymal stem cells in the treatment of inflammatory bowel diseases

X Zhang, S Wang, X Ding, J Guo… - Scandinavian journal of …, 2020 - Wiley Online Library
… for MSC preparation in cell therapy strategies for autoimmune disease. The trophic and …
Thus, based on the results of the current studies, we believe that the feasibility of combined …

Molecular mechanisms responsible for mesenchymal stem cell-based treatment of viral diseases

CR Harrell, B Popovska Jovicic, V Djonov, V Volarevic - Pathogens, 2021 - mdpi.com
… experimental studies, explored as potentially new remedy in the treatment of viral diseases
[… we summarized current knowledge on the signaling pathways and cellular mechanisms that …

Mesenchymal stem cell-derived extracellular vesicles in liver immunity and therapy

R Wu, X Fan, Y Wang, M Shen, Y Zheng… - Frontiers in …, 2022 - frontiersin.org
Mesenchymal stem cells (MSCs), also mentioned as multipotent stromal cells or mesenchymal
stromal cells, are multipotent cells present in almost all forms of postnatal organs and …