Proteomic complexity in Parkinson's disease: A redox signaling perspective of the pathophysiology and progression

M Martinez-Banaclocha - Neuroscience, 2021 - Elsevier
studies, genome-wide association studies (GWAS), and proteomic studies have shown an
increasing proteomic … and progression of this age-related neurodegenerative syndrome (…

Proteomic insights into synaptic signaling in the brain: the past, present and future

Y Xu, X Song, D Wang, Y Wang, P Li, J Li - Molecular Brain, 2021 - Springer
proteomic approaches for the study of synapses, and substantial progress has been made.
Here, we review the findings of proteomic studies of … advances in proteomics such as data-…

[HTML][HTML] Proteomes are of proteoforms: embracing the complexity

K Carbonara, M Andonovski, JR Coorssen - Proteomes, 2021 - mdpi.com
… Our goal here is to critically evaluate the current state-of-the-art in proteomics: what are
the pros and cons of available approaches, and thus what works and to what extent, what …

Aging, bone marrow and next-generation sequencing (NGS): Recent advances and future perspectives

P Ganguly, B Toghill, S Pathak - International Journal of Molecular …, 2021 - mdpi.com
… Whilst proteostasis (or protein homeostasis) serves as the quality control for maintaining the
proteome, this function is known to decline with age [8]. The loss of proteostasis leads to the …

Proteomics of host–bacterial interactions: new insights from dual perspectives

A Sukumaran, E Woroszchuk, T Ross… - Canadian Journal of …, 2021 - cdnsciencepub.com
… To begin, we present spatiotemporal proteomics of Salmonella enterica serovar
Typhimurium, a well-characterized Gram-negative bacterium that has evolved sophisticated …

[HTML][HTML] A view of the genetic and proteomic profile of extracellular matrix molecules in aging and stroke

M Chmelova, P Androvic, D Kirdajova… - Frontiers in Cellular …, 2023 - ncbi.nlm.nih.gov
… Furthermore, we compared proteomic data from 3 and 18M controls with their age-matched
animals that underwent pMCAo. Significantly altered expressions were found in Fn1 and Vtn …

Understanding the age-related alterations in the testis-specific proteome

AD Martins, JC Ribeiro, R Ferreira… - … Review of Proteomics, 2023 - Taylor & Francis
… , we present a critical overview of the studies addressing the alterations of testicular proteome
through the aging … young males to end-of-life-expectancy aged males. The comparative …

Proteomics in inherited metabolic disorders

MP Chantada-Vázquez, SB Bravo… - International Journal of …, 2022 - mdpi.com
… Here, we summarize new and emerging proteomic technologies and discuss current … of
proteomics to identify the mechanisms regulating complex IMD phenotypes; an area of research

Omics in urology: An overview on concepts, current status and future perspectives

A Panunzio, A Tafuri, A Princiotta, I Gentile… - Urologia …, 2021 - journals.sagepub.com
studies the whole of RNA molecules transcribed from the DNA (trascriptome). Proteomics
the mRNA, their structure and functions (proteome). Metabolomics addresses to the study of …

Aptamer-Based Proteomics Measuring Preoperative Cerebrospinal Fluid Protein Alterations Associated with Postoperative Delirium

ST Dillon, SM Vasunilashorn, HH Otu, L Ngo, T Fong… - Biomolecules, 2023 - mdpi.com
… Employing SomaScan proteomics analysis, we investigated the proteome of preoperative
CSF in 48 matched case–control samples from older patients undergoing elective joint …