… The key issues need to be solved in future … genome sequencing from infected human skeletal
remains dating from the Stone Age, already had most if not all the plague-related virulence …

… plague pathogen is benefitted by having additional virulence factors extending beyond its
T3SS injectosome. Although the 70-kb virulence … rooted in host genetics rather than reversion …

… of the plague bacterium from the different eras, the detected loss of a genomic region that
includes virulence-… to gain a more comprehensive understanding of all these pending issues. …

… three major plague pandemics (Justinianic, Medieval and Modern). Previous studies on …
pestis strains (including the two Danish genomes reconstructed in this study: Sejet Ødekirkegård …

… Given recent trends and plague’s resilience to control in the … and recognized virulence, it
is striking to realize that plague is … Plague circulation and population genetics of the reservoir …

… Finally, we analyzed the virulence gene profiles for all genomes by using the virulence …
available data only allow us to elucidate the most general trends. Yet, the data presented in this …

… genome of the future plague microbe is explained by the instantaneous establishment of
genomic … initial population of a plague microbe with high virulence for laboratory animals and …

… New analysis of ancient genomes reveal that … Present, which challenges the rodent-murine
ectoparasite-human model of plague transmission and historical details around plague …

… continents throughout this period, a trend not observed in other pathogens for which ancient
… In the case of the Iberian genome I2470, we observe the complete set of known virulence …

… of core issues, such as the origin of three historical plague pandemics … virulence. In scientific
literature there are no descriptions of outbreaks of plague, where the strains of the plague …