… endosomal compartments of hematopoietic immune cells, is … and thereby induce innate
immune responses. Inflammatory … , resulting in the activation of nuclear factor of activated T cells, …

… upon interaction with the immune system, inducing an innate immune response. The … LPS
to activate both TLR-2- and TLR-4-dependent signalling, whereas ultrapure LPS activated …

… inflammasome activation is necessary for transduction of signals to the immune system in …
mitis in modulating immune response may be closely related to specific external stimuli and …

… to either aid with immune recognition and activation or to help … posttranslational modification
of TLR2 within an intracellular … actinomycetemcomitans and Porphyromonas gingivalis [47]. …

… which the highest IL-36γ expression occurred needed to be established. After establishment
of … to activate an innate immune response in response to T. denticola. We found TLR2 to be …

… of manipulating the immune response as a therapeutic … associated with periodontitis (Porphyromonas
gingivalis (P. … Fimbriae activate NF-ĸB via TLR2 and induce production of pro-…

… immune upregulation, in which TLR4 and TLR2 are the main receptors (33, 45), so as to
trigger inflammation and immune responses … through its surface fimbriae and activates the …

… The aim of the work was to evaluate the diagnostic value of TLR2 and TLR4 expression
on … with key periodontal pathogenic species Filifactor alocis, Porphyromonas gingivalis. …

… Porphyromonas gingivalis, a periodontal pathogen, was also shown to produce BMVs that
induce NOD1 and NOD2 activation … of a TLR2 and NOD1-dependent IFN-β response (79). …

… in conclusion, play a crucial role in activating innate immunity and inflammation [2]. Furthermore…
actinomycetemcomitans enhanced the expression of NLRP3, TLR4, TLR2, and NOD2 in …