… FimH is the adhesion portion of type 1 fimbriae in … Since FimH stimulates TLR4, we hypothesize
that it may function … LPS is the most well-known TLR4 ligand that induces the maturation …

… FimH, the adhesion portion of type I fimbriae, is a highly conserved protein located on the
surface of Escherichia coli (E. coli) (19). As a toll-like receptor 4 (TLR4) ligand, FimH can …

… Thus, a novel multi-epitope protein composed of FimH, FyuA, … Molecular docking indicated
that thirty six ligand residues of … of FimH in the protein with Toll-like receptor 4 (TLR-4) on Ht29 …

… like fibrinogen or cellular ligands like ICAM- 1. This integrin gain … TLR4 which was previously
suggested as a receptor for the … of FimH to CD14 is causative for the increase in adhesion of …

… Type 1 pili-mediated adhesion to host cells is a crucial step … the effect of preventing FimH
sensing by TLR4 with TAK-018 … (CRD) of FimH, by mimicking its natural ligand, appears of great …

… domain of FimH did not activate TLR4 in vitro, indicating that FimH may … FimH is a type 1
fimbriae adhesion protein present on certain … FimH has been identified as a TLR4 ligand [10]. To …

… , TLR2 and TLR4 are recognized by various ligands (Table 1). However, … proteins including
invasin and FimH (71, 72). α3β1 binds to … Herpes simplex virus type 1 glycoprotein H binds to …

… UPEC has several types of fimbriae, among which, type 1 pili and its critical adhesin, FimH,
are … interaction with TLR4 to have the chance to induce the humoral and cellular responses. …

… type 1 fimbriae depend on the adhesion of lectin-like FimH, which is located at the tip of the
fimbrial … induced the expression of pro-inflammatory cytokines via TLR4. As StcD may exhibit …

… (TLR4) [34], all of which are expressed in the urine bladder to cause successful UTIs. FimH
as the tip adhesin of type 1 fimbriae … FimH adhesin to the flagellin of UPEC as a TLR5 ligand …