… The recognition of a given LPS may best be served by a particular allelic form of TLR4, and
this regard, human beings have greater overall levels of recombination and greater variance …

… TLR4/小鼠抵抗 LPS诱导的肾功能损伤 分别取 LPS注射前后的 WT和TLR4/小鼠血清
进 行血生化指标检测,结果如图 5a所示:LPS… 差异;注射 LPS后,WT小鼠 Urea表达水平上 调,TLR4/…

… Therefore, we started intraperitoneal injection of lipopolysaccharide from the photosynthetic
bacterium Rhodobacter sphaeroides (50 μg/kg, Invitrogen, San Diego, CA) in 200 μL saline …

… the receptor was named the Toll-like receptor 4 (TLR4) that recognizes lipopolysaccharide
(LPS) … strain C3H//HeJ as a consequence of its hyporesponsiveness to LPS in response to the …

… The extracellular domain of TLR4 forms a complex to act as the LPS-binding site of TLR4
(88, 89). TLR2 senses a wide range of PAMPs—including lipopeptides, peptidoglycan, and …

… Lipopolysaccharide (LPS) hypo-responsive TLR4-KO mice and congenitally neutropenic …
) GCSF-KO mice were studied to investigate the relative contributions of TLR4 signaling and …

… Toll-like receptor 4 (TLR4) has been reported to protect … recognition receptor that senses
mainly lipopolysaccharide (LPS) from … gene causing their hyporesponsiveness to LPS, and they …

… Toll-like receptor 4 (TLR4) is best known for its role in bacteria-produced lipopolysaccharide
recognition. Regarding female reproduction, TLR4 is expressed by murine cumulus cells …

… by LPS injection, wild type mice received transplanted kidneys from the C3H/HeJ LPS-hyporesponsive
mouse … knockout mice, but not in TLR4 knockout mice, suggesting a crucial role of …

… of a TLR4-specific ligand, lipopolysaccharide (LPS), … TLR4, the first identified human
Toll-like receptor, is the only … receptor for gram-negative bacterial lipopolysaccharide (LPS…