… affect its use for basic and translational studies, we evaluated a set of engineered single-chain …
of 874 Å 2 including eight salt bridges and 17 hydrogen bonds (Supplementary Table 4). …

… Most importantly these analyses provide essential … the impact of PTM peptides on stability of
MHC/peptide complexes… I alleles, and that form hydrogen bonds with peptide termini (Figure …

… to MHCII depends on hydrogen bonds to the peptide backbone. (… , and then the peptide-MHC
complexes are transported to … of conformational stability are essential for APL performance. …

… peptide:MHC Class I complexes (p:MHC-I) is a fundamental … likely provide an important
capacity to control infection when … p:MHC-I affinity and stability are fundamental to our ability to …

… In theory, the stability of a covalent bond between TCR and … Our results demonstrate rebinding
is not necessary for T cell … , which encodes GFP under the control of an internal ribosomal …

… peptide MHC class I binding are essentially two: (1) the length of 8–9 amino acids and (2)
an anchor of basic … genes (generated by the intrinsic instability of cancer cells and hereafter …

… We show that the intrinsic stability of a pMHCII linearly … -presentation pathway is crucial for
immune surveillance as … a network of MHCII conserved hydrogen bonds with the peptide main …

… By analyzing this fundamental immunological process … to compute peptide binding and
stability, study the granularity … highly polymorphic family of peptide-MHC complexes to seek the …

… As such, pMHC binding and stability are the key starting points towards understanding the T
… be deduced from either direct pMHC binding/stability assays or in silico prediction tools, and …

… to MHCII depends on hydrogen bonds to the peptide backbone (7)… , and then the peptide-MHC
complexes are transported to the … Antibodies are crucial for protection against infection by …