… colorectal cancer have not been fully understood. For example, cyclooxygenase-2 (COX-2)
and its … ) have been closely linked to its occurrence, progression and prognosis. However, the …

… the role of COX-2 in colorectal cancer progression in various clinical studies which are associated
with sporadic cancer, … and Hereditary nonpolyposis colorectal cancer. Furthermore, we …

… in colon cancer. … PGs in colon carcinoma lines and overexpressed in colon tumor tissue.
Here, we review the available evidence of the potential roles of those molecules in colon cancer …

… Purpose: To explore the effects of atorvastatin (ATST) on the proliferation and apoptosis
of colon cancer cells through the cyclooxygenase-2 (COX-2)/prostaglandin E2 (PGE2)/βcatenin …

… the risk of developing colon cancer and resulted in reduced multiplicity of distal colon tumors
as … the development of colon cancer (21). Taken together, PGE2 is essential in the growth of …

… play vital roles in regulating cancer development and progression. … in different types of cancer.
Understanding the regulatory … Colorectal cancer (CRC) is one of the most common human …

… In colorectal cancer (CRC), pathological factors that correlate with negative prognosis include,
among others, overexpression of cyclooxygenase‑2 (COX‑2) and abundant expression of …

… of the cyclooxygenase-2–prostaglandin E 2 pathway on gastrointestinal cancer development.
… For example, colorectal cancer (CRC) is the fourth most common malignancy and the third …

… Colorectal cancer (CRC) is the third leading cause of cancer-related death in both men
and women in the United States and also one of the most preventable malignancies. (1,2) …

… trials of low-dose aspirin and selective cyclooxygenase-2 inhibitors. A single placebo-… term
colorectal cancer prevention in patients with the Lynch syndrome. The sequential involvement …