Role of cyclooxygenase-2 in head and neck tumorigenesis

E Frejborg, T Salo, A Salem - International journal of molecular sciences, 2020 - mdpi.com
… for cancer patients. Thus, in this comprehensive review, we summarized the reported
differential expression patterns of COX-2 in different stages of head and neck carcinogenesis—…

Piperine reduces neoplastic progression in cervical cancer cells by downregulating the cyclooxygenase 2 pathway

LP Cardoso, SO de Sousa, JP Gusson-Zanetoni… - Pharmaceuticals, 2023 - mdpi.com
… effect of piperine on cervical cancer and to determine whether this effect is modulated by
the cyclooxygenase 2 (PTGS2) pathway using in vitro model of cervical cancer (HeLa, SiHa, …

[HTML][HTML] Prognostic and clinical significance of cyclooxygenase-2 overexpression in endometrial cancer: a meta-analysis

M Li, M Li, Y Wei, H Xu - Frontiers in Oncology, 2020 - frontiersin.org
… Irregular or post-menopausal bleeding can be an early symptom of endometrial cancer
that should prompt women to seek medical review, facilitating the early detection and timely …

Cyclooxygenase2 as a therapeutic target against human breast cancer: A comprehensive review

A Sahu, K Raza, D Pradhan, AK Jain… - WIREs Mechanisms of …, 2023 - Wiley Online Library
… The cyclooxygenase-2 is a key enzyme for prostanoids production implicated in inflammation
and can promotes tumor growth, cell proliferation, angiogenesis, tissue invasion of …

The expression of cyclooxygenase-2 in carcinoma of uterine cervix.

P Jain, S Singh, M Jain, M Ralli… - Clinical Cancer …, 2020 - search.ebscohost.com
carcinoma of uterine cervix using WHO criteria and to determine the differential expression
pattern of cyclooxygenase-2 (COX-2) in carcinoma cervix … ) cases of cervical carcinoma were …

[HTML][HTML] Combined chemotherapy with cyclooxygenase-2 (COX-2) inhibitors in treating human cancers: Recent advancement

S Li, M Jiang, L Wang, S Yu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
… This review discusses and summarizes recent advances in cancer control and treatment
using various antineoplastic drugs combined with COX-2 inhibitors. These combinations …

[HTML][HTML] The inflammatory profile of the tumor microenvironment, orchestrated by cyclooxygenase-2, promotes epithelial-mesenchymal transition

F Gómez-Valenzuela, E Escobar… - Frontiers in …, 2021 - frontiersin.org
… Throughout this review article, we propose signaling pathways that could dominate the
relationship between COX-2 (together with its metabolite PGE2, named COX-2/PGE2 axis) and …

[HTML][HTML] Cyclooxygenase-2 inhibitor: a potential combination strategy with immunotherapy in cancer

D Pu, L Yin, L Huang, C Qin, Y Zhou, Q Wu, Y Li… - Frontiers in …, 2021 - frontiersin.org
… PGE2 in tumor microenvironment (TME) actively triggers tumor immune … This review provides
insight into the mechanism of COX-2/… the clinical application and trials in cancer treatment. …

Interplay between cyclooxygenase2 and microRNAs in cancer

Z Gong, W Huang, B Wang… - Molecular …, 2021 - spandidos-publications.com
… vital roles in regulating cancer development and progression. The present review discusses
the … The present review discusses the role of COX-2 in cancer by targeting upregulated or …

[PDF][PDF] Study of Expression of Cyclooxygenase-2 in Cevical Intra Epithelial Neoplasia and Cervical Cancer

N Shaik - 2020 - digitallibrary.bldedu.ac.in
… Expression of cyclooxygenase-2 in cervical cancer is … effect of cyclooxygenase-2 expression
on tumor volume response in patients treated with radiotherapy for uterine cervical cancer. J …