Nature's nitrite-to-ammonia expressway, with no stop at dinitrogen

PMH Kroneck - JBIC Journal of Biological Inorganic Chemistry, 2022 - Springer
… (Sulfurospirillum deleyianum, Wolinella succinogenes) or, … the pentaheme enzyme cytochrome
c nitrite reductase (NrfA)… desulfuricans, and its structure was solved at 2.5 Å resolution [80,…

A mechanistic investigation of cytochrome c nitrite reductase catalyzed reduction of nitrite to ammonia: the search for catalytic intermediates

S Shahid - 2020 - search.proquest.com
structure from Geobacter lovleyi ccNiR (2.55 Å resolution, PDB … studies reviewed in Sections
1.6.2 and 1.6.3 provided the … of Wolinella succinogenes: cytochrome c nitrite reductase

Homology modeling and virtual characterization of cytochrome c nitrite reductase (NrfA) in three model bacteria responsible for short-circuit pathway, DNRA in the …

M Kaviraj, U Kumar, AK Nayak, S Chatterjee - World Journal of …, 2022 - Springer
… the structural homology modeling of NrfA protein in DNRA bacteria. Therefore, three model
DNRA bacteria (Escherechia coli, Wolinella succinogenes … not yet been resolved. Therefore, …

An unusual active site architecture in cytochrome c nitrite reductase NrfA-1 from Geobacter metallireducens

L Denkhaus, F Siffert, O Einsle - FEMS Microbiology Letters, 2023 - academic.oup.com
… with its unique, lysine-coordinated active site haem heterologously in Escherichia coli and
determined its three-dimensional structure by X-ray crystallography to 1.9 Å resolution. The …

Cytochrome c nitrite reductase from the bacterium Geobacter lovleyi represents a new NrfA subclass

J Campeciño, S Lagishetty, Z Wawrzak… - Journal of Biological …, 2020 - ASBMB
… Importantly, its crystal structure at 2.55-Å resolution revealed the presence of an arginine …
lovleyi represents a new subclass of cytochrome c nitrite reductase. Most genera from the …

Cytochrome c nitrite reductase and nitrous oxide reductase: two metallo enzymes of the nitrogen cycle with novel metal sites

W Schumacher, F Neese, U Hole… - Transition Metals in …, 2022 - taylorfrancis.com
nitrite reductase activity [NADH:nitrite oxidoreductase, EC 1.6.… nitrogen or proton coupling
were resolved. The intensities of … a hexa heme nitrite reductase from Wolinella succinogenes. …

The Search for the Four-electron Reduced Intermediate in the Cytochrome C Nitrite Reductase (CCNIR)-Catalyzed Reduction of Nitrite

VL Mandella - 2023 - search.proquest.com
… A recent crystal structure of ccNiR from Geobacter lovleyi (2.55 Å resolution, PDB … active
site haem group of Wolinella succinogenes cytochrome c nitrite reductase. Mol Microbiol 2002, (…

A Kinetic Investigation of the Early Steps in Cytochrome c Nitrite Reductase (ccNiR)-Catalyzed Reduction of Nitrite

S Shahid, M Ali, D Legaspi-Humiston, J Wilcoxen… - Biochemistry, 2021 - ACS Publications
… The decaheme enzyme cytochrome c nitrite reductase (ccNiR) catalyzes reduction of nitrite
to ammonium in a six-electron, eight-proton process. With a strong reductant as the electron …

Recent mechanistic developments for cytochrome c nitrite reductase, the key enzyme in the dissimilatory nitrate reduction to ammonium pathway

K Hird, JO Campeciño, N Lehnert, EL Hegg - Journal of Inorganic …, 2024 - Elsevier
… Here we discuss cytochrome c nitrite reductase's (NrfA) structure and mechanism. … Based
on crystal structures of Wolinella succinogenes and Thioalkalivibrio nitratireducens NrfAs, …

Elucidating Electron Storage and Distribution within the Pentaheme Scaffold of Cytochrome c Nitrite Reductase (NrfA)

V Sosa Alfaro, J Campeciño, M Tracy, SJ Elliott… - Biochemistry, 2021 - ACS Publications
nitrite reductase [cytochrome c nitrite reductase (CcNIR) or NrfA] from G. lovleyi. The latter
organism serves as a representative of the Geobacter genus, which consists of important soil …