Circulating cytokine levels in systemic sclerosis related interstitial lung disease and idiopathic pulmonary fibrosis

B Zheng, KJ Keen, MJ Fritzler, CJ Ryerson, P Wilcox… - Scientific Reports, 2023 - nature.com
… the levels of 87 circulating cytokines sampled from plasma in healthy controls to patients
Our secondary objective was to determine whether any of the differentially expressed cytokines

The effect of TGF-β1 polymorphisms on pulmonary disease progression in patients with cystic fibrosis

T Trojan, MA Alejandre Alcazar, G Fink… - BMC pulmonary …, 2022 - Springer
… more activation in pulmonary tissue remodeling and pulmonary fibrosis and less … cytokine
TGF-β 1 as a genetic modifier in patients with CF. We showed that genetic polymorphisms

Effect of genotype on the disease course in idiopathic pulmonary fibrosis despite antifibrotic treatment

M Sterclova, A Kishore, K Sikorova… - Biomedical …, 2021 - spandidos-publications.com
… to test the association between gene polymorphisms and the … of the gene polymorphisms
on the outcomes of patients up to … nucleotide polymorphism (SNP) (rs 2070874) on patient

[HTML][HTML] Interferon-λ3 rs12979860 can regulate inflammatory cytokines production in pulmonary fibrosis

E Hamdi, AA Bekhit, A Higazi, ABF Ahmed… - Saudi Pharmaceutical …, 2023 - Elsevier
… , may also exhibit a progressive fibrotic pattern (Case 2022). In this study, we will focus on
ILDs related to the phenotype of progressive pulmonary fibrosis, especially IPF, rheumatoid …

Circulating inflammatory cytokines and risk of idiopathic pulmonary fibrosis: a Mendelian randomization study

Q Jia, Y Lei, S Chen, S Liu, T Wang, Y Cheng - BMC Pulmonary Medicine, 2023 - Springer
… to idiopathic pulmonary fibrosis (IPF). However, it was still unclear whether there were casual
associations between circulating inflammatory cytokines and … of circulating cytokines were …

Targeting growth factor and cytokine pathways to treat idiopathic pulmonary fibrosis

H Ma, S Liu, S Li, Y Xia - Frontiers in Pharmacology, 2022 - frontiersin.org
… One of the novelties of this review is giving an extensive description of the multiple roles of
cytokine and growth factor pathways in pulmonary fibrosis, which provide new insights into …

[PDF][PDF] Genetic variations in idiopathic pulmonary fibrosis and patient response to pirfenidone

A Kubbara, WH Amundson, A Herman, AM Lee… - Heliyon, 2023 - cell.com
Cytokine gene polymorphisms and serum cytokine levels in patients with idiopathic pulmonary
fibrosis. … Association of HLA and cytokine gene polymorphisms with idiopathic pulmonary

Genetic Variation in CCL18 Gene Influences CCL18 Expression and Correlates with Survival in Idiopathic Pulmonary Fibrosis—Part B

C Caliskan, B Seeliger, B Jäger, J Fuge… - Journal of Clinical …, 2020 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a … levels in two independent replication cohorts. In
addition, we show the predictive value of CCL18 serum levels with respect to outcome in patients

[HTML][HTML] Distinct TNF-alpha and HLA polymorphisms associate with fibrotic and non-fibrotic subtypes of hypersensitivity pneumonitis

C Freitas, B Lima, N Melo, P Mota, H Novais-Bastos… - Pulmonology, 2023 - Elsevier
… TNF-α –308 gene polymorphisms in 40 patients with HP due to … essential for the development
of lung fibrosis. In human … mRNA transcription and higher levels of this cytokine than the G …

Molecular biomarkers in idiopathic pulmonary fibrosis: state of the art and future directions

A Stainer, P Faverio, S Busnelli, M Catalano… - International Journal of …, 2021 - mdpi.com
… Another candidate gene for IPF is ELMOD-2, expressed in alveolar macrophages … pulmonary
fibrosis in Finland showed reduced levels of mRNA expression of ELMOD-2 in IPF patients