The IL-1 family cytokines and receptors in autoimmune diseases

P Migliorini, P Italiani, F Pratesi, I Puxeddu… - Autoimmunity …, 2020 - Elsevier
… of IL-1 family cytokines in autoimmunity involves a deeper … Thus, we expect that IL-1 cytokines
may be pathogenic only … of IL-1 family cytokines in autoimmune and chronic inflammatory …

Cytokines and transcription factors in the differentiation of CD4+ T helper cell subsets and induction of tissue inflammation and autoimmunity

M Pawlak, AW Ho, VK Kuchroo - Current opinion in immunology, 2020 - Elsevier
autoimmunity in multiple experimental autoimmune disease models [7]. However, loss of the
signature cytokine IFN-γ renders mice still susceptible to autoimmunity [8,… autoimmunity and …

IL-6 in inflammation, autoimmunity and cancer

T Hirano - International immunology, 2021 - academic.oup.com
… diseases, autoimmune diseases and cancer) and even in the cytokine storm of … the cytokine
storm are uncontrolled inflammatory responses. Non-immune and immune cells, cytokines

[HTML][HTML] NF-κB: at the borders of autoimmunity and inflammation

L Barnabei, E Laplantine, W Mbongo… - Frontiers in …, 2021 - frontiersin.org
… Figure 2 Mechanisms responsible for autoimmunity involving IL-1R and TNFR. IL-1 and
TNFα are proinflammatory cytokines able to promote systemic inflammation. Activation of the …

Autoinflammation and autoimmunity across rheumatic and musculoskeletal diseases

Z Szekanecz, IB McInnes, G Schett… - Nature Reviews …, 2021 - nature.com
… of SpA with mutations in ERAP1 (also known as ARTS1, encoding endoplasmic reticulum
aminopeptidase 1) and with MHC class I suggest that T cells interact with cytokine pathways, …

The complex role of adipokines in obesity, inflammation, and autoimmunity

EB Taylor - Clinical Science, 2021 - portlandpress.com
autoimmune conditions is a response to the chronic elevations in inflammatory cytokines
ratios of each form in autoimmune diseases to gain a better understanding of adiponectin in …

[HTML][HTML] Interleukin-18 cytokine in immunity, inflammation, and autoimmunity: Biological role in induction, regulation, and treatment

SA Ihim, SD Abubakar, Z Zian, T Sasaki… - Frontiers in …, 2022 - frontiersin.org
cytokine has a role in the progression or development of some inflammatory and autoimmune
… on immune cells have revealed its potential role in inflammatory and autoimmune diseases…

Cytokine regulation and function in T cells

C Dong - Annual review of immunology, 2021 - annualreviews.org
… various cytokines has become powerful in treating immune disorders, from autoimmunity to
… While Th1 cells are frequently elevated in autoimmune diseases, Th2 cells have been well …

[HTML][HTML] Autoantibodies against cytokines: phenocopies of primary immunodeficiencies?

CL Ku, CY Chi, H von Bernuth, R Doffinger - Human Genetics, 2020 - Springer
… Anti-cytokine autoantibodies may cause immunodeficiency and have been recently recognized
as ‘autoimmune … By blocking the cytokine’s biological function, patients with anti-cytokine

[HTML][HTML] Cytokine release syndrome in COVID-19 patients, a new scenario for an old concern: the fragile balance between infections and autoimmunity

A Picchianti Diamanti, MM Rosado, C Pioli… - International journal of …, 2020 - mdpi.com
On 7 January 2020, researchers isolated and sequenced in China from patients with severe
pneumonitis a novel coronavirus, then called SARS-CoV-2, which rapidly spread worldwide…