… However, most trials involved patients with advanced-stage disease, which might not …
cytokine and anti-cytokine approaches to cancer therapy herein. Clinical trials of cytokine therapy …

… for inhibiting STAT3 as a therapeutic target in cancer cells. … Since GC is a heterogeneous
disease, advances in … of STAT3 through the secretion of several cytokines, eg, Interleukin-10, …

… The limitations of existing treatment options has led to a … With advances in our understanding
of the molecular pathways … HGF is a multifunctional cytokine that has been implicated in the …

… (T H )2 cytokines and ILC3s produce T H 17 cytokines 1,2 . NK … therapeutic target to modulate
NK cell numbers in the TME. … and limitations of NK cell–based therapeutic approaches …

… There were few developments in the use of tumor … 1980s involving the application of cytokines
for stimulating immune … lyse target cells, and can secrete cytokines and induce target cell …

… cytokines have great therapeutic potential, and some are currently being tested as therapeutic
targets in … of IL-13 and MDSCs in limiting the efficacy of CIK cell therapy in advanced HCC. …

… -target effects and the introduction of new mutations, the advantages of gene therapy such
… make it one of the most promising new medical developments of this century [101]. Moreover…

… Moreover, HCC generally presents at an advanced stage … Finally, we discuss the limitations
of the current models used … granulopoiesis via the release of cytokines such as granulocyte–…

… targets were reviewed, and the update of the progress of … uncontrolled “cytokine storm”
with hyperinflammatory cytokines, … The advantages, disadvantages, and optimal strategies of …

… basis of reference supporting the advantages of TCMs, which … In this review, we first
discuss the current progress in … The abnormally increased levels of inflammatory cytokines, …