Sepsis is a leading cause of death in intensive care units and survivors develop prolonged
immunosuppression and a high incidence of recurrent infections. No definitive therapy exists …

… potential applications of MDSCs as biomarkers and targets for clinical treatment of sepsis. …
For concomitant immunosuppression, the causative view is lymphocyte exhaustion and …

… Remarkably, anti-inflammatory therapies such as cytokine … These results led to a new
perspective on sepsis management, and … as a therapeutic target for sepsis research [115]. During …

… incorporated view of the synchronization of the cytokine storm … Interleukin [IL]-10 is a potent
immunoregulatory molecule … and is a potential therapeutic target in sepsis. Science. 2015;347…

… In view of this, a recent study has devoted to provide accurate global sepsis estimates by
analyzing both in and out-hospital sepsis… cytokines also showed diverse immunoregulatory role …

… focuses upon release, impact, and potential therapy of a limited number of potent anti-inflammatory
cytokines. … This view is supported by studies examining specific organ failures in …

… production of inflammatory cytokines, displaying a pro… immunoregulation. These cells present
captured exogenous antigens to T cells and secrete costimulatory molecules and cytokines…

… aimed to show the new therapeutic targets in sepsis treatment with current studies. New
clinical … inflammatory response in sepsis can contribute to the understanding of the symptoms. …

… , A., Chavakis, T., Weitz, J., Hofer, S., & Weigand, MA Interleukin-3 amplifies acute inflammation
and is a potential therapeutic target in sepsis. Science, (2015). 347(6227), 1260–1265. …

… development of new diagnostic and therapeutic targets. This … of SAKI, with a view to finding
new targets for SAKI treatment. … and anti-inflammatory cytokines, and is closely related to the …