… With the advent of gene expression profiling and remarkable … The expression patterns
of master regulators across subtypes … expressed between survivor groups in any subtypes. …

… The remaining clinical profiles, molecular subtypes, and … explore the distribution of methylation
subtypes in pan-glioma, as shown … that IGFBP2 is associated with cancer-related immune …

… and IGFBP2 are age related genes, and highly expressed in old … The DNA methylation profile
of age related genes in glioma … We found that DNA methylation intensity of EMP3 gene was …

… 2HG leads to global DNA hypermethylation by restricting the … revealed that E2F7 binds to
EZH2 promoter, activating its … NFIA/IGFBP2 inhibition in order to induce death of glioma cells […

… were used to target Ezh2 gene expression in BV2 microglia and … factor binding according
to individual subtype. The WNT-β, … Our data showed increased levels of IGFBP2 produced by …

… Meanwhile, the gene expression profile of the control (non-… mesenchymal subtypes of
gliomas expressed higher levels of … IGFBP2 is highly likely to be the oncogenic gene of glioma. …

… form of DNA methylation (N6-mA) in glioblastoma that occurs … specimens infers glioblastoma
transcriptional subtypes, … family epigenetic regulator EZH2 predominates and drives a …

… , reduced global DNA methylation, referred to as glioma CpG … DNA methylome profiling
using the Heidelberg methylation … , thus, confirm lower levels of global DNA methylation as a …

… GBs depicted methylation profiles akin to either low-grade gliomas or PXA and … subtype
or grade. In the present study, unsupervised hierarchal clustering of mRNA expression profiles …

… changes such as differential DNA methylation patterns [13]. These … Mechanistically, increased
EZH2 expression favours lineage … IGFBP2 [155]. These results, together with the increased …