[HTML][HTML] Navigating the DNA methylation landscape of cancer
A Nishiyama, M Nakanishi - Trends in Genetics, 2021 - cell.com
… of a model in which aberrant DNA methylation promotes cellular … mechanisms of DNA
methylation abnormalities in cancer as … important for chromatin binding of DNA methyltransferase (…
methylation abnormalities in cancer as … important for chromatin binding of DNA methyltransferase (…
DNA methylation in ovarian cancer susceptibility
BM Reid, BL Fridley - Cancers, 2020 - mdpi.com
… inheritance of cancer susceptibility was functionally authenticated in a mouse model where
the deletion of chromatin … of DNA methylation and their known role in cancer development …
the deletion of chromatin … of DNA methylation and their known role in cancer development …
Mitotic inheritance of DNA methylation: more than just copy and paste
X Ming, B Zhu, Y Li - Journal of Genetics and Genomics, 2021 - Elsevier
… This review focuses on the maintenance of DNA methylation … the mechanisms for the
inheritance of DNA methylation as a … chromatin remodeler that functions by promoting methylation …
inheritance of DNA methylation as a … chromatin remodeler that functions by promoting methylation …
Kinetics and mechanisms of mitotic inheritance of DNA methylation and their roles in aging-associated methylome deterioration
… the maintenance machinery, 20 chromatin likely acts as a barrier to DNA methylation. …
Moreover, many aberrant DNA methylation changes in cancer also occur during aging, and …
Moreover, many aberrant DNA methylation changes in cancer also occur during aging, and …
Epigenome chaos: stochastic and deterministic DNA methylation events drive cancer evolution
G Russo, A Tramontano, I Iodice, L Chiariotti, A Pezone - Cancers, 2021 - mdpi.com
… tumor evolution. Epigenetic changes, aberrant DNA methylation and modifications of chromatin
… Disordered changes of DNA methylation profiles are the hallmarks of all cancer types, …
… Disordered changes of DNA methylation profiles are the hallmarks of all cancer types, …
The role of DNA methylation and DNA methyltransferases in cancer
DJ Weisenberger, R Lakshminarasimhan… - DNA Methyltransferases …, 2022 - Springer
… the aberrant DNA methylation changes in human cancers and how … Aside from CpG island
promoter DNA hypermethylation-… , where DNA methylation contributes to a “closed” chromatin …
promoter DNA hypermethylation-… , where DNA methylation contributes to a “closed” chromatin …
Analytical and therapeutic profiles of DNA methylation alterations in cancer; an overview of changes in chromatin arrangement and alterations in histone surfaces
SE Norollahi, S Vahidi, S Shams… - … molecular biology and …, 2023 - degruyter.com
… DNA methylation structures in cancer are altered, with three procedures by which DNA
methylation helps cancer … of the cancer genome, and also focal hypermethylation of the promoters …
methylation helps cancer … of the cancer genome, and also focal hypermethylation of the promoters …
The interplay between DNA and histone methylation: molecular mechanisms and disease implications
… is how DNA methylation machineries interact with other chromatin … DNA methylation has
demonstrated synergy in cancer therapy. In gastric cancer, inhibition of EZH2 following DNA …
demonstrated synergy in cancer therapy. In gastric cancer, inhibition of EZH2 following DNA …
Epigenetic modifications in gastric cancer: Focus on DNA methylation
V Ebrahimi, A Soleimanian, T Ebrahimi, R Azargun… - Gene, 2020 - Elsevier
… Then, we discuss other epigenetic alterations in gastric cancer including: Histon modification,
chromatin remodeling and non-coding RNAs. Finally, we highlight clinical applications of …
chromatin remodeling and non-coding RNAs. Finally, we highlight clinical applications of …
Effect of aberrant DNA methylation on cancer stem cell properties
… Cancer Stem Cells (CSCs) are minor populations of tumor … DNA methylation accumulation
affects self-renewal, differentiation, multidrug-resistant, and metastasis processes in cancer …
affects self-renewal, differentiation, multidrug-resistant, and metastasis processes in cancer …
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